![5-{4-[(Difluoromethyl)sulfanyl]benzyl}-1,3-thiazol-2-amine structure](/static/products/327/327105-95-3.png)
5-{4-[(Difluoromethyl)sulfanyl]benzyl}-1,3-thiazol-2-amine
TL;DR: 5-{4-[(Difluoromethyl)sulfanyl]benzyl}-1,3-thiazol-2-amine (CAS 327105-95-3) is a chemical compound with molecular formula C11H10F2N2S2 and molecular weight 272.03 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
5-[[4-(difluoromethylsulfanyl)phenyl]methyl]-1,3-thiazol-2-amine
Also Known As: 5-{4-[(difluoromethyl)sulfanyl]benzyl}-1,3-thiazol-2-amine, 2-amino-5-(4-difluoromethylsulfanylbenzyl)-1,3-thiazole, 5-[[4-(difluoromethylsulfanyl)phenyl]methyl]-1,3-thiazol-2-amine, 5-{[4-(difluoromethylthio)phenyl]methyl}-1,3-thiazole-2-ylamine
| Molecular Formula | C11H10F2N2S2 |
|---|---|
| Molecular Weight | 272.03 g/mol |
| LogP | 3.6308 |
| Topological Polar Surface Area | 38.91 Ų |
| Hydrogen Bond Donors | 1 |
| Hydrogen Bond Acceptors | 4 |
| Rotatable Bonds | 4 |
| Exact Mass | 272.02536 |
| Heavy Atoms | 17 |
| Complexity | 482.4716 |
Chemical Identifiers
| CAS Number | 327105-95-3 |
|---|---|
| SMILES | C1=CC(=CC=C1CC2=CN=C(S2)N)SC(F)F |
Product Overview
5-{4-[(Difluoromethyl)sulfanyl]benzyl}-1,3-thiazol-2-amine (CAS 327105-95-3), with molecular formula C11H10F2N2S2 and molecular weight 272.03 g/mol. IUPAC: 5-[[4-(difluoromethylsulfanyl)phenyl]methyl]-1,3-thiazol-2-amine.
Chemical Property Profile of 5-{4-[(Difluoromethyl)sulfanyl]benzyl}-1,3-thiazol-2-amine
Property Insights of 5-{4-[(Difluoromethyl)sulfanyl]benzyl}-1,3-thiazol-2-amine
The XLogP value of 3.6308 indicates that 5-{4-[(Difluoromethyl)sulfanyl]benzyl}-1,3-thiazol-2-amine is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. With a topological polar surface area (TPSA) of 38.91 Ų, 5-{4-[(Difluoromethyl)sulfanyl]benzyl}-1,3-thiazol-2-amine exhibits relatively low polarity, potentially indicating favorable cell membrane permeability. Following Lipinski's Rule of Five, 5-{4-[(Difluoromethyl)sulfanyl]benzyl}-1,3-thiazol-2-amine has 1 hydrogen bond donor(s) and 4 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of 5-{4-[(Difluoromethyl)sulfanyl]benzyl}-1,3-thiazol-2-amine?
The CAS number of 5-{4-[(Difluoromethyl)sulfanyl]benzyl}-1,3-thiazol-2-amine is 327105-95-3.
What is the molecular formula of 5-{4-[(Difluoromethyl)sulfanyl]benzyl}-1,3-thiazol-2-amine?
The molecular formula of 5-{4-[(Difluoromethyl)sulfanyl]benzyl}-1,3-thiazol-2-amine is C11H10F2N2S2.
What is the molecular weight of 5-{4-[(Difluoromethyl)sulfanyl]benzyl}-1,3-thiazol-2-amine?
The molecular weight of 5-{4-[(Difluoromethyl)sulfanyl]benzyl}-1,3-thiazol-2-amine is 272.03 g/mol.
Where can I buy 5-{4-[(Difluoromethyl)sulfanyl]benzyl}-1,3-thiazol-2-amine?
You can request a quote for 5-{4-[(Difluoromethyl)sulfanyl]benzyl}-1,3-thiazol-2-amine directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for 5-{4-[(Difluoromethyl)sulfanyl]benzyl}-1,3-thiazol-2-amine?
Yes, KEHONG BIO provides custom synthesis services for 5-{4-[(Difluoromethyl)sulfanyl]benzyl}-1,3-thiazol-2-amine and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.