AE-848/11733027 structure

AE-848/11733027

TL;DR: AE-848/11733027 (CAS 327101-23-5) is a chemical compound with molecular formula C24H18FN3O and molecular weight 383.14 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.

1-(cyclopropanecarbonyl)-2-(4-fluorophenyl)-2,3a-dihydro-1H-pyrrolo[1,2-a]quinoline-3,3-dicarbonitrile

Also Known As: AE-848/11733027, 1-(cyclopropanecarbonyl)-2-(4-fluorophenyl)-2,3a-dihydro-1H-pyrrolo[1,2-a]quinoline-3,3-dicarbonitrile, 1-(cyclopropylcarbonyl)-2-(4-fluorophenyl)-1,2-dihydropyrrolo[1,2-a]quinoline-3,3(3aH)-dicarbonitrile, 1-(cyclopropanecarbonyl)-2-(4-fluorophenyl)-1,2-dihydropyrrolo[1,2-a]quinoline-3,3(3aH)-dicarbonitrile

CAS: 327101-23-5
Molecular Formula C24H18FN3O
Molecular Weight 383.14 g/mol
LogP 4.20616
Topological Polar Surface Area 67.89 Ų
Hydrogen Bond Donors 0
Hydrogen Bond Acceptors 4
Rotatable Bonds 3
Exact Mass 383.1434
Heavy Atoms 29
Complexity 1090.181

Chemical Identifiers

CAS Number 327101-23-5
SMILES C1CC1C(=O)C2C(C(C3N2C4=CC=CC=C4C=C3)(C#N)C#N)C5=CC=C(C=C5)F

Product Overview

AE-848/11733027 (CAS 327101-23-5), with molecular formula C24H18FN3O and molecular weight 383.14 g/mol. IUPAC: 1-(cyclopropanecarbonyl)-2-(4-fluorophenyl)-2,3a-dihydro-1H-pyrrolo[1,2-a]quinoline-3,3-dicarbonitrile.

🧪
Safety Data Sheet (MSDS / SDS) View the Laboratory Chemical Safety Summary (LCSS) on PubChem — includes GHS classifications, hazard statements, first aid measures, and handling precautions.
View MSDS →

Chemical Property Profile of AE-848/11733027

XLogP
4.20616
TPSA (Topological Polar Surface Area)
67.89
Hydrogen Bond Donors
0
Hydrogen Bond Acceptors
4
Rotatable Bonds
3
Heavy Atoms
29
Complexity
1090.181
Exact Mass
383.1434
Monoisotopic Mass
383.1434
Data Source: Chemical property values are referenced from PubChem, the world's largest open chemistry database maintained by the National Center for Biotechnology Information (NCBI), U.S. National Library of Medicine.

Property Insights of AE-848/11733027

The XLogP value of 4.20616 indicates that AE-848/11733027 is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. The TPSA of 67.89 Ų falls within the moderate polarity range, balancing permeability and solubility for AE-848/11733027. Following Lipinski's Rule of Five, AE-848/11733027 has 0 hydrogen bond donor(s) and 4 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.

Frequently Asked Questions

What is the typical lead time for this product?
Lead time typically ranges from 3-7 business days for in-stock items. For larger quantities or custom orders, please contact us for specific lead times.
Can you provide samples for testing?
Yes, we offer sample quantities for quality testing. Please submit an inquiry with your requirements and we will arrange samples accordingly.
What documentation do you provide with the product?
We provide COA (Certificate of Analysis), MSDS (Material Safety Data Sheet), and technical data sheets with each shipment.
Do you ship internationally?
Yes, we ship to most countries worldwide. Shipping costs and delivery times vary by location. Please contact us for specific shipping information.

Frequently Asked Questions

What is the CAS number of AE-848/11733027?

The CAS number of AE-848/11733027 is 327101-23-5.

What is the molecular formula of AE-848/11733027?

The molecular formula of AE-848/11733027 is C24H18FN3O.

What is the molecular weight of AE-848/11733027?

The molecular weight of AE-848/11733027 is 383.14 g/mol.

Where can I buy AE-848/11733027?

You can request a quote for AE-848/11733027 directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.

Does KEHONG BIO offer custom synthesis for AE-848/11733027?

Yes, KEHONG BIO provides custom synthesis services for AE-848/11733027 and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.

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