5-chloro-4-(4-chlorobenzenesulfonyl)-N-(2,4-difluorophenyl)-1,3-thiazol-2-amine
TL;DR: 5-chloro-4-(4-chlorobenzenesulfonyl)-N-(2,4-difluorophenyl)-1,3-thiazol-2-amine (CAS 327081-71-0) is a chemical compound with molecular formula C15H8Cl2F2N2O2S2 and molecular weight 419.94 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
5-chloro-4-(4-chlorophenyl)sulfonyl-N-(2,4-difluorophenyl)-1,3-thiazol-2-amine
Also Known As: 5-chloro-4-(4-chlorobenzenesulfonyl)-N-(2,4-difluorophenyl)-1,3-thiazol-2-amine, 5-chloro-4-(4-chlorophenyl)sulfonyl-N-(2,4-difluorophenyl)-1,3-thiazol-2-amine
| Molecular Formula | C15H8Cl2F2N2O2S2 |
|---|---|
| Molecular Weight | 419.94 g/mol |
| LogP | 5.3045 |
| Topological Polar Surface Area | 59.06 Ų |
| Hydrogen Bond Donors | 1 |
| Hydrogen Bond Acceptors | 5 |
| Rotatable Bonds | 4 |
| Exact Mass | 419.93723 |
| Heavy Atoms | 25 |
| Complexity | 1038.1849 |
Chemical Identifiers
| CAS Number | 327081-71-0 |
|---|---|
| SMILES | C1=CC(=CC=C1S(=O)(=O)C2=C(SC(=N2)NC3=C(C=C(C=C3)F)F)Cl)Cl |
Product Overview
5-chloro-4-(4-chlorobenzenesulfonyl)-N-(2,4-difluorophenyl)-1,3-thiazol-2-amine (CAS 327081-71-0), with molecular formula C15H8Cl2F2N2O2S2 and molecular weight 419.94 g/mol. IUPAC: 5-chloro-4-(4-chlorophenyl)sulfonyl-N-(2,4-difluorophenyl)-1,3-thiazol-2-amine.
Chemical Property Profile of 5-chloro-4-(4-chlorobenzenesulfonyl)-N-(2,4-difluorophenyl)-1,3-thiazol-2-amine
Property Insights of 5-chloro-4-(4-chlorobenzenesulfonyl)-N-(2,4-difluorophenyl)-1,3-thiazol-2-amine
The XLogP value of 5.3045 indicates that 5-chloro-4-(4-chlorobenzenesulfonyl)-N-(2,4-difluorophenyl)-1,3-thiazol-2-amine is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. With a topological polar surface area (TPSA) of 59.06 Ų, 5-chloro-4-(4-chlorobenzenesulfonyl)-N-(2,4-difluorophenyl)-1,3-thiazol-2-amine exhibits relatively low polarity, potentially indicating favorable cell membrane permeability. Following Lipinski's Rule of Five, 5-chloro-4-(4-chlorobenzenesulfonyl)-N-(2,4-difluorophenyl)-1,3-thiazol-2-amine has 1 hydrogen bond donor(s) and 5 hydrogen bond acceptor(s), which may warrant consideration for formulation optimization.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of 5-chloro-4-(4-chlorobenzenesulfonyl)-N-(2,4-difluorophenyl)-1,3-thiazol-2-amine?
The CAS number of 5-chloro-4-(4-chlorobenzenesulfonyl)-N-(2,4-difluorophenyl)-1,3-thiazol-2-amine is 327081-71-0.
What is the molecular formula of 5-chloro-4-(4-chlorobenzenesulfonyl)-N-(2,4-difluorophenyl)-1,3-thiazol-2-amine?
The molecular formula of 5-chloro-4-(4-chlorobenzenesulfonyl)-N-(2,4-difluorophenyl)-1,3-thiazol-2-amine is C15H8Cl2F2N2O2S2.
What is the molecular weight of 5-chloro-4-(4-chlorobenzenesulfonyl)-N-(2,4-difluorophenyl)-1,3-thiazol-2-amine?
The molecular weight of 5-chloro-4-(4-chlorobenzenesulfonyl)-N-(2,4-difluorophenyl)-1,3-thiazol-2-amine is 419.94 g/mol.
Where can I buy 5-chloro-4-(4-chlorobenzenesulfonyl)-N-(2,4-difluorophenyl)-1,3-thiazol-2-amine?
You can request a quote for 5-chloro-4-(4-chlorobenzenesulfonyl)-N-(2,4-difluorophenyl)-1,3-thiazol-2-amine directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for 5-chloro-4-(4-chlorobenzenesulfonyl)-N-(2,4-difluorophenyl)-1,3-thiazol-2-amine?
Yes, KEHONG BIO provides custom synthesis services for 5-chloro-4-(4-chlorobenzenesulfonyl)-N-(2,4-difluorophenyl)-1,3-thiazol-2-amine and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.