N-(4,5-dimethyl-1,3-thiazol-2-yl)-2-fluorobenzamide
TL;DR: N-(4,5-dimethyl-1,3-thiazol-2-yl)-2-fluorobenzamide (CAS 327078-80-8) is a chemical compound with molecular formula C12H11FN2OS and molecular weight 250.06 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
N-(4,5-dimethyl-1,3-thiazol-2-yl)-2-fluorobenzamide
Also Known As: Benzamide,N- -2-fluoro-, N-(4,5-dimethyl-1,3-thiazol-2-yl)-2-fluorobenzamide, BENZAMIDE, N-(4,5-DIMETHYL-2-THIAZOLYL)-2-FLUORO-, benzamide,N-(4,5-dimethyl-2-thiazolyl)-2-fluoro-, Benzamide, N-(4,5-dimethyl-2-thiazolyl)-2-fluoro- (9CI)
| Molecular Formula | C12H11FN2OS |
|---|---|
| Molecular Weight | 250.06 g/mol |
| LogP | 3.15134 |
| Topological Polar Surface Area | 41.99 Ų |
| Hydrogen Bond Donors | 1 |
| Hydrogen Bond Acceptors | 3 |
| Rotatable Bonds | 2 |
| Exact Mass | 250.05762 |
| Heavy Atoms | 17 |
| Complexity | 545.8833 |
Chemical Identifiers
| CAS Number | 327078-80-8 |
|---|---|
| SMILES | CC1=C(SC(=N1)NC(=O)C2=CC=CC=C2F)C |
Product Overview
N-(4,5-dimethyl-1,3-thiazol-2-yl)-2-fluorobenzamide (CAS 327078-80-8), with molecular formula C12H11FN2OS and molecular weight 250.06 g/mol. IUPAC: N-(4,5-dimethyl-1,3-thiazol-2-yl)-2-fluorobenzamide.
Chemical Property Profile of N-(4,5-dimethyl-1,3-thiazol-2-yl)-2-fluorobenzamide
Property Insights of N-(4,5-dimethyl-1,3-thiazol-2-yl)-2-fluorobenzamide
The XLogP value of 3.15134 indicates that N-(4,5-dimethyl-1,3-thiazol-2-yl)-2-fluorobenzamide is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. With a topological polar surface area (TPSA) of 41.99 Ų, N-(4,5-dimethyl-1,3-thiazol-2-yl)-2-fluorobenzamide exhibits relatively low polarity, potentially indicating favorable cell membrane permeability. Following Lipinski's Rule of Five, N-(4,5-dimethyl-1,3-thiazol-2-yl)-2-fluorobenzamide has 1 hydrogen bond donor(s) and 3 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of N-(4,5-dimethyl-1,3-thiazol-2-yl)-2-fluorobenzamide?
The CAS number of N-(4,5-dimethyl-1,3-thiazol-2-yl)-2-fluorobenzamide is 327078-80-8.
What is the molecular formula of N-(4,5-dimethyl-1,3-thiazol-2-yl)-2-fluorobenzamide?
The molecular formula of N-(4,5-dimethyl-1,3-thiazol-2-yl)-2-fluorobenzamide is C12H11FN2OS.
What is the molecular weight of N-(4,5-dimethyl-1,3-thiazol-2-yl)-2-fluorobenzamide?
The molecular weight of N-(4,5-dimethyl-1,3-thiazol-2-yl)-2-fluorobenzamide is 250.06 g/mol.
Where can I buy N-(4,5-dimethyl-1,3-thiazol-2-yl)-2-fluorobenzamide?
You can request a quote for N-(4,5-dimethyl-1,3-thiazol-2-yl)-2-fluorobenzamide directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for N-(4,5-dimethyl-1,3-thiazol-2-yl)-2-fluorobenzamide?
Yes, KEHONG BIO provides custom synthesis services for N-(4,5-dimethyl-1,3-thiazol-2-yl)-2-fluorobenzamide and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.