(Z)-2-Cyano-N-(2-cyano-ethyl)-N-(4-methoxy-phenyl)-3-thiophen-2-yl-acrylamide structure

(Z)-2-Cyano-N-(2-cyano-ethyl)-N-(4-methoxy-phenyl)-3-thiophen-2-yl-acrylamide

TL;DR: (Z)-2-Cyano-N-(2-cyano-ethyl)-N-(4-methoxy-phenyl)-3-thiophen-2-yl-acrylamide (CAS 327077-42-9) is a chemical compound with molecular formula C18H15N3O2S and molecular weight 337.09 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.

(Z)-2-cyano-N-(2-cyanoethyl)-N-(4-methoxyphenyl)-3-thiophen-2-ylprop-2-enamide

Also Known As: BAS 02766716, (Z)-2-Cyano-N-(2-cyano-ethyl)-N-(4-methoxy-phenyl)-3-thiophen-2-yl-acrylamide, (Z)-2-cyano-N-(2-cyanoethyl)-N-(4-methoxyphenyl)-3-(thiophen-2-yl)acrylamide, (Z)-2-cyano-N-(2-cyanoethyl)-N-(4-methoxyphenyl)-3-thiophen-2-ylprop-2-enamide

CAS: 327077-42-9
Molecular Formula C18H15N3O2S
Molecular Weight 337.09 g/mol
LogP 3.61056
Topological Polar Surface Area 77.12 Ų
Hydrogen Bond Donors 0
Hydrogen Bond Acceptors 5
Rotatable Bonds 6
Exact Mass 337.0885
Heavy Atoms 24
Complexity 796.27966

Chemical Identifiers

CAS Number 327077-42-9
SMILES COC1=CC=C(C=C1)N(CCC#N)C(=O)/C(=C\C2=CC=CS2)/C#N

Product Overview

(Z)-2-Cyano-N-(2-cyano-ethyl)-N-(4-methoxy-phenyl)-3-thiophen-2-yl-acrylamide (CAS 327077-42-9), with molecular formula C18H15N3O2S and molecular weight 337.09 g/mol. IUPAC: (Z)-2-cyano-N-(2-cyanoethyl)-N-(4-methoxyphenyl)-3-thiophen-2-ylprop-2-enamide.

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Safety Data Sheet (MSDS / SDS) View the Laboratory Chemical Safety Summary (LCSS) on PubChem — includes GHS classifications, hazard statements, first aid measures, and handling precautions.
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Chemical Property Profile of (Z)-2-Cyano-N-(2-cyano-ethyl)-N-(4-methoxy-phenyl)-3-thiophen-2-yl-acrylamide

XLogP
3.61056
TPSA (Topological Polar Surface Area)
77.12
Hydrogen Bond Donors
0
Hydrogen Bond Acceptors
5
Rotatable Bonds
6
Heavy Atoms
24
Complexity
796.27966
Exact Mass
337.0885
Monoisotopic Mass
337.0885
Data Source: Chemical property values are referenced from PubChem, the world's largest open chemistry database maintained by the National Center for Biotechnology Information (NCBI), U.S. National Library of Medicine.

Property Insights of (Z)-2-Cyano-N-(2-cyano-ethyl)-N-(4-methoxy-phenyl)-3-thiophen-2-yl-acrylamide

The XLogP value of 3.61056 indicates that (Z)-2-Cyano-N-(2-cyano-ethyl)-N-(4-methoxy-phenyl)-3-thiophen-2-yl-acrylamide is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. The TPSA of 77.12 Ų falls within the moderate polarity range, balancing permeability and solubility for (Z)-2-Cyano-N-(2-cyano-ethyl)-N-(4-methoxy-phenyl)-3-thiophen-2-yl-acrylamide. Following Lipinski's Rule of Five, (Z)-2-Cyano-N-(2-cyano-ethyl)-N-(4-methoxy-phenyl)-3-thiophen-2-yl-acrylamide has 0 hydrogen bond donor(s) and 5 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.

Frequently Asked Questions

What is the typical lead time for this product?
Lead time typically ranges from 3-7 business days for in-stock items. For larger quantities or custom orders, please contact us for specific lead times.
Can you provide samples for testing?
Yes, we offer sample quantities for quality testing. Please submit an inquiry with your requirements and we will arrange samples accordingly.
What documentation do you provide with the product?
We provide COA (Certificate of Analysis), MSDS (Material Safety Data Sheet), and technical data sheets with each shipment.
Do you ship internationally?
Yes, we ship to most countries worldwide. Shipping costs and delivery times vary by location. Please contact us for specific shipping information.

Frequently Asked Questions

What is the CAS number of (Z)-2-Cyano-N-(2-cyano-ethyl)-N-(4-methoxy-phenyl)-3-thiophen-2-yl-acrylamide?

The CAS number of (Z)-2-Cyano-N-(2-cyano-ethyl)-N-(4-methoxy-phenyl)-3-thiophen-2-yl-acrylamide is 327077-42-9.

What is the molecular formula of (Z)-2-Cyano-N-(2-cyano-ethyl)-N-(4-methoxy-phenyl)-3-thiophen-2-yl-acrylamide?

The molecular formula of (Z)-2-Cyano-N-(2-cyano-ethyl)-N-(4-methoxy-phenyl)-3-thiophen-2-yl-acrylamide is C18H15N3O2S.

What is the molecular weight of (Z)-2-Cyano-N-(2-cyano-ethyl)-N-(4-methoxy-phenyl)-3-thiophen-2-yl-acrylamide?

The molecular weight of (Z)-2-Cyano-N-(2-cyano-ethyl)-N-(4-methoxy-phenyl)-3-thiophen-2-yl-acrylamide is 337.09 g/mol.

Where can I buy (Z)-2-Cyano-N-(2-cyano-ethyl)-N-(4-methoxy-phenyl)-3-thiophen-2-yl-acrylamide?

You can request a quote for (Z)-2-Cyano-N-(2-cyano-ethyl)-N-(4-methoxy-phenyl)-3-thiophen-2-yl-acrylamide directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.

Does KEHONG BIO offer custom synthesis for (Z)-2-Cyano-N-(2-cyano-ethyl)-N-(4-methoxy-phenyl)-3-thiophen-2-yl-acrylamide?

Yes, KEHONG BIO provides custom synthesis services for (Z)-2-Cyano-N-(2-cyano-ethyl)-N-(4-methoxy-phenyl)-3-thiophen-2-yl-acrylamide and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.

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