(E)-2-cyano-N-(2-methoxyphenyl)-3-(1-methyl-1H-indol-3-yl)acrylamide
TL;DR: (E)-2-cyano-N-(2-methoxyphenyl)-3-(1-methyl-1H-indol-3-yl)acrylamide (CAS 327076-77-7) is a chemical compound with molecular formula C20H17N3O2 and molecular weight 331.13 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
(E)-2-cyano-N-(2-methoxyphenyl)-3-(1-methylindol-3-yl)prop-2-enamide
Also Known As: (E)-2-cyano-N-(2-methoxyphenyl)-3-(1-methyl-1H-indol-3-yl)acrylamide, F1118-0511, (E)-2-cyano-N-(2-methoxyphenyl)-3-(1-methylindol-3-yl)prop-2-enamide, N-o-methoxyphenyl-(E)-2-cyano-3-(1-methyl-3-indolyl)acrylamide, (2E)-2-cyano-N-(2-methoxyphenyl)-3-(1-methylindol-3-yl)prop-2-enamide
| Molecular Formula | C20H17N3O2 |
|---|---|
| Molecular Weight | 331.13 g/mol |
| LogP | 3.7 |
| Topological Polar Surface Area | 67.1 Ų |
| Hydrogen Bond Donors | 1 |
| Hydrogen Bond Acceptors | 3 |
| Rotatable Bonds | 4 |
| Exact Mass | 331.13208 |
| Heavy Atoms | 25 |
| Complexity | 565.0 |
Chemical Identifiers
| CAS Number | 327076-77-7 |
|---|---|
| SMILES | CN1C=C(C2=CC=CC=C21)/C=C(\C#N)/C(=O)NC3=CC=CC=C3OC |
| InChIKey | CJEARCWBDTZGRU-SDNWHVSQSA-N |
Product Overview
(E)-2-cyano-N-(2-methoxyphenyl)-3-(1-methyl-1H-indol-3-yl)acrylamide (CAS 327076-77-7), with molecular formula C20H17N3O2 and molecular weight 331.13 g/mol. IUPAC: (E)-2-cyano-N-(2-methoxyphenyl)-3-(1-methylindol-3-yl)prop-2-enamide.
Chemical Property Profile of (E)-2-cyano-N-(2-methoxyphenyl)-3-(1-methyl-1H-indol-3-yl)acrylamide
Property Insights of (E)-2-cyano-N-(2-methoxyphenyl)-3-(1-methyl-1H-indol-3-yl)acrylamide
The XLogP value of 3.7 indicates that (E)-2-cyano-N-(2-methoxyphenyl)-3-(1-methyl-1H-indol-3-yl)acrylamide is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. The TPSA of 67.1 Ų falls within the moderate polarity range, balancing permeability and solubility for (E)-2-cyano-N-(2-methoxyphenyl)-3-(1-methyl-1H-indol-3-yl)acrylamide. Following Lipinski's Rule of Five, (E)-2-cyano-N-(2-methoxyphenyl)-3-(1-methyl-1H-indol-3-yl)acrylamide has 1 hydrogen bond donor(s) and 3 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of (E)-2-cyano-N-(2-methoxyphenyl)-3-(1-methyl-1H-indol-3-yl)acrylamide?
The CAS number of (E)-2-cyano-N-(2-methoxyphenyl)-3-(1-methyl-1H-indol-3-yl)acrylamide is 327076-77-7.
What is the molecular formula of (E)-2-cyano-N-(2-methoxyphenyl)-3-(1-methyl-1H-indol-3-yl)acrylamide?
The molecular formula of (E)-2-cyano-N-(2-methoxyphenyl)-3-(1-methyl-1H-indol-3-yl)acrylamide is C20H17N3O2.
What is the molecular weight of (E)-2-cyano-N-(2-methoxyphenyl)-3-(1-methyl-1H-indol-3-yl)acrylamide?
The molecular weight of (E)-2-cyano-N-(2-methoxyphenyl)-3-(1-methyl-1H-indol-3-yl)acrylamide is 331.13 g/mol.
Where can I buy (E)-2-cyano-N-(2-methoxyphenyl)-3-(1-methyl-1H-indol-3-yl)acrylamide?
You can request a quote for (E)-2-cyano-N-(2-methoxyphenyl)-3-(1-methyl-1H-indol-3-yl)acrylamide directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for (E)-2-cyano-N-(2-methoxyphenyl)-3-(1-methyl-1H-indol-3-yl)acrylamide?
Yes, KEHONG BIO provides custom synthesis services for (E)-2-cyano-N-(2-methoxyphenyl)-3-(1-methyl-1H-indol-3-yl)acrylamide and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.