(E)-2-cyano-3-(1H-indol-3-yl)-N-(3-nitrophenyl)acrylamide
TL;DR: (E)-2-cyano-3-(1H-indol-3-yl)-N-(3-nitrophenyl)acrylamide (CAS 327076-67-5) is a chemical compound with molecular formula C18H12N4O3 and molecular weight 332.09 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
(E)-2-cyano-3-(1H-indol-3-yl)-N-(3-nitrophenyl)prop-2-enamide
Also Known As: (E)-2-cyano-3-(1H-indol-3-yl)-N-(3-nitrophenyl)acrylamide, AB00673320-01, F1118-0495, (2E)-2-cyano-3-indol-3-yl-N-(3-nitrophenyl)prop-2-enamide, (2E)-2-cyano-3-(1H-indol-3-yl)-N-(3-nitrophenyl)prop-2-enamide
| Molecular Formula | C18H12N4O3 |
|---|---|
| Molecular Weight | 332.09 g/mol |
| LogP | 3.62178 |
| Topological Polar Surface Area | 111.82 Ų |
| Hydrogen Bond Donors | 2 |
| Hydrogen Bond Acceptors | 4 |
| Rotatable Bonds | 4 |
| Exact Mass | 332.09094 |
| Heavy Atoms | 25 |
| Complexity | 1043.6559 |
Chemical Identifiers
| CAS Number | 327076-67-5 |
|---|---|
| SMILES | C1=CC=C2C(=C1)C(=CN2)/C=C(\C#N)/C(=O)NC3=CC(=CC=C3)[N+](=O)[O-] |
Product Overview
(E)-2-cyano-3-(1H-indol-3-yl)-N-(3-nitrophenyl)acrylamide (CAS 327076-67-5), with molecular formula C18H12N4O3 and molecular weight 332.09 g/mol. IUPAC: (E)-2-cyano-3-(1H-indol-3-yl)-N-(3-nitrophenyl)prop-2-enamide.
Chemical Property Profile of (E)-2-cyano-3-(1H-indol-3-yl)-N-(3-nitrophenyl)acrylamide
Property Insights of (E)-2-cyano-3-(1H-indol-3-yl)-N-(3-nitrophenyl)acrylamide
The XLogP value of 3.62178 indicates that (E)-2-cyano-3-(1H-indol-3-yl)-N-(3-nitrophenyl)acrylamide is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. The TPSA of 111.82 Ų falls within the moderate polarity range, balancing permeability and solubility for (E)-2-cyano-3-(1H-indol-3-yl)-N-(3-nitrophenyl)acrylamide. Following Lipinski's Rule of Five, (E)-2-cyano-3-(1H-indol-3-yl)-N-(3-nitrophenyl)acrylamide has 2 hydrogen bond donor(s) and 4 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of (E)-2-cyano-3-(1H-indol-3-yl)-N-(3-nitrophenyl)acrylamide?
The CAS number of (E)-2-cyano-3-(1H-indol-3-yl)-N-(3-nitrophenyl)acrylamide is 327076-67-5.
What is the molecular formula of (E)-2-cyano-3-(1H-indol-3-yl)-N-(3-nitrophenyl)acrylamide?
The molecular formula of (E)-2-cyano-3-(1H-indol-3-yl)-N-(3-nitrophenyl)acrylamide is C18H12N4O3.
What is the molecular weight of (E)-2-cyano-3-(1H-indol-3-yl)-N-(3-nitrophenyl)acrylamide?
The molecular weight of (E)-2-cyano-3-(1H-indol-3-yl)-N-(3-nitrophenyl)acrylamide is 332.09 g/mol.
Where can I buy (E)-2-cyano-3-(1H-indol-3-yl)-N-(3-nitrophenyl)acrylamide?
You can request a quote for (E)-2-cyano-3-(1H-indol-3-yl)-N-(3-nitrophenyl)acrylamide directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for (E)-2-cyano-3-(1H-indol-3-yl)-N-(3-nitrophenyl)acrylamide?
Yes, KEHONG BIO provides custom synthesis services for (E)-2-cyano-3-(1H-indol-3-yl)-N-(3-nitrophenyl)acrylamide and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.