(E)-N-(2-chlorophenyl)-2-cyano-3-(1H-indol-3-yl)acrylamide
TL;DR: (E)-N-(2-chlorophenyl)-2-cyano-3-(1H-indol-3-yl)acrylamide (CAS 327076-65-3) is a chemical compound with molecular formula C18H12ClN3O and molecular weight 321.07 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
(E)-N-(2-chlorophenyl)-2-cyano-3-(1H-indol-3-yl)prop-2-enamide
Also Known As: (E)-N-(2-chlorophenyl)-2-cyano-3-(1H-indol-3-yl)acrylamide, (2E)-N-(2-chlorophenyl)-2-cyano-3-(1H-indol-3-yl)prop-2-enamide, F1118-0493, (E)-N-(2-chlorophenyl)-2-cyano-3-(1H-indol-3-yl)prop-2-enamide, (2E)-N-(2-chlorophenyl)-2-cyano-3-indol-3-ylprop-2-enamide
| Molecular Formula | C18H12ClN3O |
|---|---|
| Molecular Weight | 321.07 g/mol |
| LogP | 4.4 |
| Topological Polar Surface Area | 68.7 Ų |
| Hydrogen Bond Donors | 2 |
| Hydrogen Bond Acceptors | 2 |
| Rotatable Bonds | 3 |
| Exact Mass | 321.0669 |
| Heavy Atoms | 23 |
| Complexity | 524.0 |
Chemical Identifiers
| CAS Number | 327076-65-3 |
|---|---|
| SMILES | C1=CC=C2C(=C1)C(=CN2)/C=C(\C#N)/C(=O)NC3=CC=CC=C3Cl |
| InChIKey | UWAGOVNYEUQWBU-FMIVXFBMSA-N |
Product Overview
(E)-N-(2-chlorophenyl)-2-cyano-3-(1H-indol-3-yl)acrylamide (CAS 327076-65-3), with molecular formula C18H12ClN3O and molecular weight 321.07 g/mol. IUPAC: (E)-N-(2-chlorophenyl)-2-cyano-3-(1H-indol-3-yl)prop-2-enamide.
Chemical Property Profile of (E)-N-(2-chlorophenyl)-2-cyano-3-(1H-indol-3-yl)acrylamide
Property Insights of (E)-N-(2-chlorophenyl)-2-cyano-3-(1H-indol-3-yl)acrylamide
The XLogP value of 4.4 indicates that (E)-N-(2-chlorophenyl)-2-cyano-3-(1H-indol-3-yl)acrylamide is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. The TPSA of 68.7 Ų falls within the moderate polarity range, balancing permeability and solubility for (E)-N-(2-chlorophenyl)-2-cyano-3-(1H-indol-3-yl)acrylamide. Following Lipinski's Rule of Five, (E)-N-(2-chlorophenyl)-2-cyano-3-(1H-indol-3-yl)acrylamide has 2 hydrogen bond donor(s) and 2 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of (E)-N-(2-chlorophenyl)-2-cyano-3-(1H-indol-3-yl)acrylamide?
The CAS number of (E)-N-(2-chlorophenyl)-2-cyano-3-(1H-indol-3-yl)acrylamide is 327076-65-3.
What is the molecular formula of (E)-N-(2-chlorophenyl)-2-cyano-3-(1H-indol-3-yl)acrylamide?
The molecular formula of (E)-N-(2-chlorophenyl)-2-cyano-3-(1H-indol-3-yl)acrylamide is C18H12ClN3O.
What is the molecular weight of (E)-N-(2-chlorophenyl)-2-cyano-3-(1H-indol-3-yl)acrylamide?
The molecular weight of (E)-N-(2-chlorophenyl)-2-cyano-3-(1H-indol-3-yl)acrylamide is 321.07 g/mol.
Where can I buy (E)-N-(2-chlorophenyl)-2-cyano-3-(1H-indol-3-yl)acrylamide?
You can request a quote for (E)-N-(2-chlorophenyl)-2-cyano-3-(1H-indol-3-yl)acrylamide directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for (E)-N-(2-chlorophenyl)-2-cyano-3-(1H-indol-3-yl)acrylamide?
Yes, KEHONG BIO provides custom synthesis services for (E)-N-(2-chlorophenyl)-2-cyano-3-(1H-indol-3-yl)acrylamide and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.