![(5E)-3-[[4-(3-chlorophenyl)piperazin-1-yl]methyl]-5-[(4-dimethylaminophenyl)methylidene]-2-sulfanylidene-1,3-thiazolidin-4-one structure](/static/products/3270/327076-16-4.webp)
(5E)-3-[[4-(3-chlorophenyl)piperazin-1-yl]methyl]-5-[(4-dimethylaminophenyl)methylidene]-2-sulfanylidene-1,3-thiazolidin-4-one
TL;DR: (5E)-3-[[4-(3-chlorophenyl)piperazin-1-yl]methyl]-5-[(4-dimethylaminophenyl)methylidene]-2-sulfanylidene-1,3-thiazolidin-4-one (CAS 327076-16-4) is a chemical compound with molecular formula C23H25ClN4OS2 and molecular weight 472.12 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
(5E)-3-[[4-(3-chlorophenyl)piperazin-1-yl]methyl]-5-[[4-(dimethylamino)phenyl]methylidene]-2-sulfanylidene-1,3-thiazolidin-4-one
Also Known As: (5E)-3-[[4-(3-chlorophenyl)piperazin-1-yl]methyl]-5-[(4-dimethylaminophenyl)methylidene]-2-sulfanylidene-1,3-thiazolidin-4-one, (5E)-3-[[4-(3-chlorophenyl)piperazin-1-yl]methyl]-5-[[4-(dimethylamino)phenyl]methylidene]-2-sulfanylidene-1,3-thiazolidin-4-one, (5E)-3-{[4-(3-chlorophenyl)piperazin-1-yl]methyl}-5-[4-(dimethylamino)benzylidene]-2-thioxo-1,3-thiazolidin-4-one, (E)-3-((4-(3-chlorophenyl)piperazin-1-yl)methyl)-5-(4-(dimethylamino)benzylidene)-2-thioxothiazolidin-4-one
| Molecular Formula | C23H25ClN4OS2 |
|---|---|
| Molecular Weight | 472.12 g/mol |
| LogP | 4.3869 |
| Topological Polar Surface Area | 30.03 Ų |
| Hydrogen Bond Donors | 0 |
| Hydrogen Bond Acceptors | 6 |
| Rotatable Bonds | 5 |
| Exact Mass | 472.11584 |
| Heavy Atoms | 31 |
| Complexity | 1000.891 |
Chemical Identifiers
| CAS Number | 327076-16-4 |
|---|---|
| SMILES | CN(C)C1=CC=C(C=C1)/C=C/2\C(=O)N(C(=S)S2)CN3CCN(CC3)C4=CC(=CC=C4)Cl |
Product Overview
(5E)-3-[[4-(3-chlorophenyl)piperazin-1-yl]methyl]-5-[(4-dimethylaminophenyl)methylidene]-2-sulfanylidene-1,3-thiazolidin-4-one (CAS 327076-16-4), with molecular formula C23H25ClN4OS2 and molecular weight 472.12 g/mol. IUPAC: (5E)-3-[[4-(3-chlorophenyl)piperazin-1-yl]methyl]-5-[[4-(dimethylamino)phenyl]methylidene]-2-sulfanylidene-1,3-thiazolidin-4-one.
Chemical Property Profile of (5E)-3-[[4-(3-chlorophenyl)piperazin-1-yl]methyl]-5-[(4-dimethylaminophenyl)methylidene]-2-sulfanylidene-1,3-thiazolidin-4-one
Property Insights of (5E)-3-[[4-(3-chlorophenyl)piperazin-1-yl]methyl]-5-[(4-dimethylaminophenyl)methylidene]-2-sulfanylidene-1,3-thiazolidin-4-one
The XLogP value of 4.3869 indicates that (5E)-3-[[4-(3-chlorophenyl)piperazin-1-yl]methyl]-5-[(4-dimethylaminophenyl)methylidene]-2-sulfanylidene-1,3-thiazolidin-4-one is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. With a topological polar surface area (TPSA) of 30.03 Ų, (5E)-3-[[4-(3-chlorophenyl)piperazin-1-yl]methyl]-5-[(4-dimethylaminophenyl)methylidene]-2-sulfanylidene-1,3-thiazolidin-4-one exhibits relatively low polarity, potentially indicating favorable cell membrane permeability. Following Lipinski's Rule of Five, (5E)-3-[[4-(3-chlorophenyl)piperazin-1-yl]methyl]-5-[(4-dimethylaminophenyl)methylidene]-2-sulfanylidene-1,3-thiazolidin-4-one has 0 hydrogen bond donor(s) and 6 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of (5E)-3-[[4-(3-chlorophenyl)piperazin-1-yl]methyl]-5-[(4-dimethylaminophenyl)methylidene]-2-sulfanylidene-1,3-thiazolidin-4-one?
The CAS number of (5E)-3-[[4-(3-chlorophenyl)piperazin-1-yl]methyl]-5-[(4-dimethylaminophenyl)methylidene]-2-sulfanylidene-1,3-thiazolidin-4-one is 327076-16-4.
What is the molecular formula of (5E)-3-[[4-(3-chlorophenyl)piperazin-1-yl]methyl]-5-[(4-dimethylaminophenyl)methylidene]-2-sulfanylidene-1,3-thiazolidin-4-one?
The molecular formula of (5E)-3-[[4-(3-chlorophenyl)piperazin-1-yl]methyl]-5-[(4-dimethylaminophenyl)methylidene]-2-sulfanylidene-1,3-thiazolidin-4-one is C23H25ClN4OS2.
What is the molecular weight of (5E)-3-[[4-(3-chlorophenyl)piperazin-1-yl]methyl]-5-[(4-dimethylaminophenyl)methylidene]-2-sulfanylidene-1,3-thiazolidin-4-one?
The molecular weight of (5E)-3-[[4-(3-chlorophenyl)piperazin-1-yl]methyl]-5-[(4-dimethylaminophenyl)methylidene]-2-sulfanylidene-1,3-thiazolidin-4-one is 472.12 g/mol.
Where can I buy (5E)-3-[[4-(3-chlorophenyl)piperazin-1-yl]methyl]-5-[(4-dimethylaminophenyl)methylidene]-2-sulfanylidene-1,3-thiazolidin-4-one?
You can request a quote for (5E)-3-[[4-(3-chlorophenyl)piperazin-1-yl]methyl]-5-[(4-dimethylaminophenyl)methylidene]-2-sulfanylidene-1,3-thiazolidin-4-one directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for (5E)-3-[[4-(3-chlorophenyl)piperazin-1-yl]methyl]-5-[(4-dimethylaminophenyl)methylidene]-2-sulfanylidene-1,3-thiazolidin-4-one?
Yes, KEHONG BIO provides custom synthesis services for (5E)-3-[[4-(3-chlorophenyl)piperazin-1-yl]methyl]-5-[(4-dimethylaminophenyl)methylidene]-2-sulfanylidene-1,3-thiazolidin-4-one and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.