![(Z)-ethyl 5-(4-(dimethylamino)phenyl)-2-(3-ethoxy-4-hydroxybenzylidene)-7-methyl-3-oxo-3,5-dihydro-2H-thiazolo[3,2-a]pyrimidine-6-carboxylate structure](/static/products/3270/327055-87-8.webp)
(Z)-ethyl 5-(4-(dimethylamino)phenyl)-2-(3-ethoxy-4-hydroxybenzylidene)-7-methyl-3-oxo-3,5-dihydro-2H-thiazolo[3,2-a]pyrimidine-6-carboxylate
TL;DR: (Z)-ethyl 5-(4-(dimethylamino)phenyl)-2-(3-ethoxy-4-hydroxybenzylidene)-7-methyl-3-oxo-3,5-dihydro-2H-thiazolo[3,2-a]pyrimidine-6-carboxylate (CAS 327055-87-8) is a chemical compound with molecular formula C27H29N3O5S and molecular weight 507.18 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
ethyl (2Z)-5-[4-(dimethylamino)phenyl]-2-[(3-ethoxy-4-hydroxyphenyl)methylidene]-7-methyl-3-oxo-5H-[1,3]thiazolo[3,2-a]pyrimidine-6-carboxylate
Also Known As: (Z)-ethyl 5-(4-(dimethylamino)phenyl)-2-(3-ethoxy-4-hydroxybenzylidene)-7-methyl-3-oxo-3,5-dihydro-2H-thiazolo[3,2-a]pyrimidine-6-carboxylate, ethyl (2Z)-5-(4-dimethylaminophenyl)-2-[(3-ethoxy-4-hydroxyphenyl)methylidene]-7-methyl-3-oxo-5H-[1,3]thiazolo[3,2-a]pyrimidine-6-carboxylate, ethyl (2Z)-5-[4-(dimethylamino)phenyl]-2-(3-ethoxy-4-hydroxybenzylidene)-7-methyl-3-oxo-2,3-dihydro-5H-[1,3]thiazolo[3,2-a]pyrimidine-6-carboxylate, ETHYL (2Z)-5-[4-(DIMETHYLAMINO)PHENYL]-2-[(3-ETHOXY-4-HYDROXYPHENYL)METHYLIDENE]-7-METHYL-3-OXO-2H,3H,5H-[1,3]THIAZOLO[3,2-A]PYRIMIDINE-6-CARBOXYLATE, ETHYL (2Z)-5-[4-(DIMETHYLAMINO)PHENYL]-2-[(3-ETHOXY-4-HYDROXYPHENYL)METHYLIDENE]-7-METHYL-3-OXO-5H-[1,3]THIAZOLO[3,2-A]PYRIMIDINE-6-CARBOXYLATE
| Molecular Formula | C27H29N3O5S |
|---|---|
| Molecular Weight | 507.18 g/mol |
| LogP | 2.9686 |
| Topological Polar Surface Area | 93.36 Ų |
| Hydrogen Bond Donors | 1 |
| Hydrogen Bond Acceptors | 8 |
| Rotatable Bonds | 7 |
| Exact Mass | 507.1828 |
| Heavy Atoms | 36 |
| Complexity | 1499.5818 |
Chemical Identifiers
| CAS Number | 327055-87-8 |
|---|---|
| SMILES | CCOC1=C(C=CC(=C1)/C=C\2/C(=O)N3C(C(=C(N=C3S2)C)C(=O)OCC)C4=CC=C(C=C4)N(C)C)O |
Product Overview
(Z)-ethyl 5-(4-(dimethylamino)phenyl)-2-(3-ethoxy-4-hydroxybenzylidene)-7-methyl-3-oxo-3,5-dihydro-2H-thiazolo[3,2-a]pyrimidine-6-carboxylate (CAS 327055-87-8), with molecular formula C27H29N3O5S and molecular weight 507.18 g/mol. IUPAC: ethyl (2Z)-5-[4-(dimethylamino)phenyl]-2-[(3-ethoxy-4-hydroxyphenyl)methylidene]-7-methyl-3-oxo-5H-[1,3]thiazolo[3,2-a]pyrimidine-6-carboxylate.
Chemical Property Profile of (Z)-ethyl 5-(4-(dimethylamino)phenyl)-2-(3-ethoxy-4-hydroxybenzylidene)-7-methyl-3-oxo-3,5-dihydro-2H-thiazolo[3,2-a]pyrimidine-6-carboxylate
Property Insights of (Z)-ethyl 5-(4-(dimethylamino)phenyl)-2-(3-ethoxy-4-hydroxybenzylidene)-7-methyl-3-oxo-3,5-dihydro-2H-thiazolo[3,2-a]pyrimidine-6-carboxylate
The XLogP value of 2.9686 suggests moderate lipophilicity, balancing water solubility and membrane permeability for (Z)-ethyl 5-(4-(dimethylamino)phenyl)-2-(3-ethoxy-4-hydroxybenzylidene)-7-methyl-3-oxo-3,5-dihydro-2H-thiazolo[3,2-a]pyrimidine-6-carboxylate. The TPSA of 93.36 Ų falls within the moderate polarity range, balancing permeability and solubility for (Z)-ethyl 5-(4-(dimethylamino)phenyl)-2-(3-ethoxy-4-hydroxybenzylidene)-7-methyl-3-oxo-3,5-dihydro-2H-thiazolo[3,2-a]pyrimidine-6-carboxylate. Following Lipinski's Rule of Five, (Z)-ethyl 5-(4-(dimethylamino)phenyl)-2-(3-ethoxy-4-hydroxybenzylidene)-7-methyl-3-oxo-3,5-dihydro-2H-thiazolo[3,2-a]pyrimidine-6-carboxylate has 1 hydrogen bond donor(s) and 8 hydrogen bond acceptor(s), which may warrant consideration for formulation optimization.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of (Z)-ethyl 5-(4-(dimethylamino)phenyl)-2-(3-ethoxy-4-hydroxybenzylidene)-7-methyl-3-oxo-3,5-dihydro-2H-thiazolo[3,2-a]pyrimidine-6-carboxylate?
The CAS number of (Z)-ethyl 5-(4-(dimethylamino)phenyl)-2-(3-ethoxy-4-hydroxybenzylidene)-7-methyl-3-oxo-3,5-dihydro-2H-thiazolo[3,2-a]pyrimidine-6-carboxylate is 327055-87-8.
What is the molecular formula of (Z)-ethyl 5-(4-(dimethylamino)phenyl)-2-(3-ethoxy-4-hydroxybenzylidene)-7-methyl-3-oxo-3,5-dihydro-2H-thiazolo[3,2-a]pyrimidine-6-carboxylate?
The molecular formula of (Z)-ethyl 5-(4-(dimethylamino)phenyl)-2-(3-ethoxy-4-hydroxybenzylidene)-7-methyl-3-oxo-3,5-dihydro-2H-thiazolo[3,2-a]pyrimidine-6-carboxylate is C27H29N3O5S.
What is the molecular weight of (Z)-ethyl 5-(4-(dimethylamino)phenyl)-2-(3-ethoxy-4-hydroxybenzylidene)-7-methyl-3-oxo-3,5-dihydro-2H-thiazolo[3,2-a]pyrimidine-6-carboxylate?
The molecular weight of (Z)-ethyl 5-(4-(dimethylamino)phenyl)-2-(3-ethoxy-4-hydroxybenzylidene)-7-methyl-3-oxo-3,5-dihydro-2H-thiazolo[3,2-a]pyrimidine-6-carboxylate is 507.18 g/mol.
Where can I buy (Z)-ethyl 5-(4-(dimethylamino)phenyl)-2-(3-ethoxy-4-hydroxybenzylidene)-7-methyl-3-oxo-3,5-dihydro-2H-thiazolo[3,2-a]pyrimidine-6-carboxylate?
You can request a quote for (Z)-ethyl 5-(4-(dimethylamino)phenyl)-2-(3-ethoxy-4-hydroxybenzylidene)-7-methyl-3-oxo-3,5-dihydro-2H-thiazolo[3,2-a]pyrimidine-6-carboxylate directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for (Z)-ethyl 5-(4-(dimethylamino)phenyl)-2-(3-ethoxy-4-hydroxybenzylidene)-7-methyl-3-oxo-3,5-dihydro-2H-thiazolo[3,2-a]pyrimidine-6-carboxylate?
Yes, KEHONG BIO provides custom synthesis services for (Z)-ethyl 5-(4-(dimethylamino)phenyl)-2-(3-ethoxy-4-hydroxybenzylidene)-7-methyl-3-oxo-3,5-dihydro-2H-thiazolo[3,2-a]pyrimidine-6-carboxylate and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.