6-(Trifluoromethyl)-1H-indole-2-carboxylic acid
TL;DR: 6-(Trifluoromethyl)-1H-indole-2-carboxylic acid (CAS 327-20-8) is a chemical compound with molecular formula C10H6F3NO2 and molecular weight 229.04 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
6-(trifluoromethyl)-1H-indole-2-carboxylic acid
Also Known As: 6-(Trifluoromethyl)-1H-indole-2-carboxylic acid, 6-(Trifluoromethyl)indole-2-carboxylic acid, 6-Trifluoromethyl-1H-indole-2-carboxylic acid, 2-(4-Hydroxyphenylazo)benzoicacid, 6-(Trifluoromethyl)-2-indole carboxylic acid
| Molecular Formula | C10H6F3NO2 |
|---|---|
| Molecular Weight | 229.04 g/mol |
| LogP | 2.8849 |
| Topological Polar Surface Area | 53.09 Ų |
| Hydrogen Bond Donors | 2 |
| Hydrogen Bond Acceptors | 1 |
| Rotatable Bonds | 1 |
| Exact Mass | 229.03506 |
| Heavy Atoms | 16 |
| Complexity | 556.67975 |
Chemical Identifiers
| CAS Number | 327-20-8 |
|---|---|
| SMILES | C1=CC2=C(C=C1C(F)(F)F)NC(=C2)C(=O)O |
Product Overview
6-(Trifluoromethyl)-1H-indole-2-carboxylic acid (CAS 327-20-8), with molecular formula C10H6F3NO2 and molecular weight 229.04 g/mol. IUPAC: 6-(trifluoromethyl)-1H-indole-2-carboxylic acid.
Chemical Property Profile of 6-(Trifluoromethyl)-1H-indole-2-carboxylic acid
Property Insights of 6-(Trifluoromethyl)-1H-indole-2-carboxylic acid
The XLogP value of 2.8849 suggests moderate lipophilicity, balancing water solubility and membrane permeability for 6-(Trifluoromethyl)-1H-indole-2-carboxylic acid. With a topological polar surface area (TPSA) of 53.09 Ų, 6-(Trifluoromethyl)-1H-indole-2-carboxylic acid exhibits relatively low polarity, potentially indicating favorable cell membrane permeability. Following Lipinski's Rule of Five, 6-(Trifluoromethyl)-1H-indole-2-carboxylic acid has 2 hydrogen bond donor(s) and 1 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of 6-(Trifluoromethyl)-1H-indole-2-carboxylic acid?
The CAS number of 6-(Trifluoromethyl)-1H-indole-2-carboxylic acid is 327-20-8.
What is the molecular formula of 6-(Trifluoromethyl)-1H-indole-2-carboxylic acid?
The molecular formula of 6-(Trifluoromethyl)-1H-indole-2-carboxylic acid is C10H6F3NO2.
What is the molecular weight of 6-(Trifluoromethyl)-1H-indole-2-carboxylic acid?
The molecular weight of 6-(Trifluoromethyl)-1H-indole-2-carboxylic acid is 229.04 g/mol.
Where can I buy 6-(Trifluoromethyl)-1H-indole-2-carboxylic acid?
You can request a quote for 6-(Trifluoromethyl)-1H-indole-2-carboxylic acid directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for 6-(Trifluoromethyl)-1H-indole-2-carboxylic acid?
Yes, KEHONG BIO provides custom synthesis services for 6-(Trifluoromethyl)-1H-indole-2-carboxylic acid and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.