![5-[[4-(Difluoromethoxy)phenyl]methylene]-3-[(tetrahydro-2-furanyl)methyl]-2-thioxo-4-thiazolidinone structure](/static/products/3268/326871-47-0.webp)
5-[[4-(Difluoromethoxy)phenyl]methylene]-3-[(tetrahydro-2-furanyl)methyl]-2-thioxo-4-thiazolidinone
TL;DR: 5-[[4-(Difluoromethoxy)phenyl]methylene]-3-[(tetrahydro-2-furanyl)methyl]-2-thioxo-4-thiazolidinone (CAS 326871-47-0) is a chemical compound with molecular formula C16H15F2NO3S2 and molecular weight 371.05 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
5-[[4-(difluoromethoxy)phenyl]methylidene]-3-(oxolan-2-ylmethyl)-2-sulfanylidene-1,3-thiazolidin-4-one
Also Known As: 5-[[4-(Difluoromethoxy)phenyl]methylene]-3-[(tetrahydro-2-furanyl)methyl]-2-thioxo-4-thiazolidinone, 5-[[4-(difluoromethoxy)phenyl]methylidene]-3-(oxolan-2-ylmethyl)-2-sulfanylidene-1,3-thiazolidin-4-one, 5-{[4-(Difluoromethoxy)phenyl]methylidene}-3-[(oxolan-2-yl)methyl]-2-sulfanylidene-1,3-thiazolidin-4-one
| Molecular Formula | C16H15F2NO3S2 |
|---|---|
| Molecular Weight | 371.05 g/mol |
| LogP | 3.6682 |
| Topological Polar Surface Area | 38.77 Ų |
| Hydrogen Bond Donors | 0 |
| Hydrogen Bond Acceptors | 5 |
| Rotatable Bonds | 5 |
| Exact Mass | 371.04614 |
| Heavy Atoms | 24 |
| Complexity | 657.7913 |
Chemical Identifiers
| CAS Number | 326871-47-0 |
|---|---|
| SMILES | C1CC(OC1)CN2C(=O)C(=CC3=CC=C(C=C3)OC(F)F)SC2=S |
Product Overview
5-[[4-(Difluoromethoxy)phenyl]methylene]-3-[(tetrahydro-2-furanyl)methyl]-2-thioxo-4-thiazolidinone (CAS 326871-47-0), with molecular formula C16H15F2NO3S2 and molecular weight 371.05 g/mol. IUPAC: 5-[[4-(difluoromethoxy)phenyl]methylidene]-3-(oxolan-2-ylmethyl)-2-sulfanylidene-1,3-thiazolidin-4-one.
Chemical Property Profile of 5-[[4-(Difluoromethoxy)phenyl]methylene]-3-[(tetrahydro-2-furanyl)methyl]-2-thioxo-4-thiazolidinone
Property Insights of 5-[[4-(Difluoromethoxy)phenyl]methylene]-3-[(tetrahydro-2-furanyl)methyl]-2-thioxo-4-thiazolidinone
The XLogP value of 3.6682 indicates that 5-[[4-(Difluoromethoxy)phenyl]methylene]-3-[(tetrahydro-2-furanyl)methyl]-2-thioxo-4-thiazolidinone is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. With a topological polar surface area (TPSA) of 38.77 Ų, 5-[[4-(Difluoromethoxy)phenyl]methylene]-3-[(tetrahydro-2-furanyl)methyl]-2-thioxo-4-thiazolidinone exhibits relatively low polarity, potentially indicating favorable cell membrane permeability. Following Lipinski's Rule of Five, 5-[[4-(Difluoromethoxy)phenyl]methylene]-3-[(tetrahydro-2-furanyl)methyl]-2-thioxo-4-thiazolidinone has 0 hydrogen bond donor(s) and 5 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of 5-[[4-(Difluoromethoxy)phenyl]methylene]-3-[(tetrahydro-2-furanyl)methyl]-2-thioxo-4-thiazolidinone?
The CAS number of 5-[[4-(Difluoromethoxy)phenyl]methylene]-3-[(tetrahydro-2-furanyl)methyl]-2-thioxo-4-thiazolidinone is 326871-47-0.
What is the molecular formula of 5-[[4-(Difluoromethoxy)phenyl]methylene]-3-[(tetrahydro-2-furanyl)methyl]-2-thioxo-4-thiazolidinone?
The molecular formula of 5-[[4-(Difluoromethoxy)phenyl]methylene]-3-[(tetrahydro-2-furanyl)methyl]-2-thioxo-4-thiazolidinone is C16H15F2NO3S2.
What is the molecular weight of 5-[[4-(Difluoromethoxy)phenyl]methylene]-3-[(tetrahydro-2-furanyl)methyl]-2-thioxo-4-thiazolidinone?
The molecular weight of 5-[[4-(Difluoromethoxy)phenyl]methylene]-3-[(tetrahydro-2-furanyl)methyl]-2-thioxo-4-thiazolidinone is 371.05 g/mol.
Where can I buy 5-[[4-(Difluoromethoxy)phenyl]methylene]-3-[(tetrahydro-2-furanyl)methyl]-2-thioxo-4-thiazolidinone?
You can request a quote for 5-[[4-(Difluoromethoxy)phenyl]methylene]-3-[(tetrahydro-2-furanyl)methyl]-2-thioxo-4-thiazolidinone directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for 5-[[4-(Difluoromethoxy)phenyl]methylene]-3-[(tetrahydro-2-furanyl)methyl]-2-thioxo-4-thiazolidinone?
Yes, KEHONG BIO provides custom synthesis services for 5-[[4-(Difluoromethoxy)phenyl]methylene]-3-[(tetrahydro-2-furanyl)methyl]-2-thioxo-4-thiazolidinone and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.