![N-(1,3-dioxaindan-5-yl)-2-cyano-3-[4-(difluoromethoxy)phenyl]prop-2-enamide structure](/static/products/3266/326616-37-9.webp)
N-(1,3-dioxaindan-5-yl)-2-cyano-3-[4-(difluoromethoxy)phenyl]prop-2-enamide
TL;DR: N-(1,3-dioxaindan-5-yl)-2-cyano-3-[4-(difluoromethoxy)phenyl]prop-2-enamide (CAS 326616-37-9) is a chemical compound with molecular formula C18H12F2N2O4 and molecular weight 358.08 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
(E)-N-(1,3-benzodioxol-5-yl)-2-cyano-3-[4-(difluoromethoxy)phenyl]prop-2-enamide
Also Known As: (E)-N-(1,3-benzodioxol-5-yl)-2-cyano-3-[4-(difluoromethoxy)phenyl]prop-2-enamide, N-(1,3-dioxaindan-5-yl)-2-cyano-3-[4-(difluoromethoxy)phenyl]prop-2-enamide
| Molecular Formula | C18H12F2N2O4 |
|---|---|
| Molecular Weight | 358.08 g/mol |
| LogP | 3.56238 |
| Topological Polar Surface Area | 80.58 Ų |
| Hydrogen Bond Donors | 1 |
| Hydrogen Bond Acceptors | 5 |
| Rotatable Bonds | 5 |
| Exact Mass | 358.0765 |
| Heavy Atoms | 26 |
| Complexity | 889.0544 |
Chemical Identifiers
| CAS Number | 326616-37-9 |
|---|---|
| SMILES | C1OC2=C(O1)C=C(C=C2)NC(=O)/C(=C/C3=CC=C(C=C3)OC(F)F)/C#N |
Product Overview
N-(1,3-dioxaindan-5-yl)-2-cyano-3-[4-(difluoromethoxy)phenyl]prop-2-enamide (CAS 326616-37-9), with molecular formula C18H12F2N2O4 and molecular weight 358.08 g/mol. IUPAC: (E)-N-(1,3-benzodioxol-5-yl)-2-cyano-3-[4-(difluoromethoxy)phenyl]prop-2-enamide.
Chemical Property Profile of N-(1,3-dioxaindan-5-yl)-2-cyano-3-[4-(difluoromethoxy)phenyl]prop-2-enamide
Property Insights of N-(1,3-dioxaindan-5-yl)-2-cyano-3-[4-(difluoromethoxy)phenyl]prop-2-enamide
The XLogP value of 3.56238 indicates that N-(1,3-dioxaindan-5-yl)-2-cyano-3-[4-(difluoromethoxy)phenyl]prop-2-enamide is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. The TPSA of 80.58 Ų falls within the moderate polarity range, balancing permeability and solubility for N-(1,3-dioxaindan-5-yl)-2-cyano-3-[4-(difluoromethoxy)phenyl]prop-2-enamide. Following Lipinski's Rule of Five, N-(1,3-dioxaindan-5-yl)-2-cyano-3-[4-(difluoromethoxy)phenyl]prop-2-enamide has 1 hydrogen bond donor(s) and 5 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of N-(1,3-dioxaindan-5-yl)-2-cyano-3-[4-(difluoromethoxy)phenyl]prop-2-enamide?
The CAS number of N-(1,3-dioxaindan-5-yl)-2-cyano-3-[4-(difluoromethoxy)phenyl]prop-2-enamide is 326616-37-9.
What is the molecular formula of N-(1,3-dioxaindan-5-yl)-2-cyano-3-[4-(difluoromethoxy)phenyl]prop-2-enamide?
The molecular formula of N-(1,3-dioxaindan-5-yl)-2-cyano-3-[4-(difluoromethoxy)phenyl]prop-2-enamide is C18H12F2N2O4.
What is the molecular weight of N-(1,3-dioxaindan-5-yl)-2-cyano-3-[4-(difluoromethoxy)phenyl]prop-2-enamide?
The molecular weight of N-(1,3-dioxaindan-5-yl)-2-cyano-3-[4-(difluoromethoxy)phenyl]prop-2-enamide is 358.08 g/mol.
Where can I buy N-(1,3-dioxaindan-5-yl)-2-cyano-3-[4-(difluoromethoxy)phenyl]prop-2-enamide?
You can request a quote for N-(1,3-dioxaindan-5-yl)-2-cyano-3-[4-(difluoromethoxy)phenyl]prop-2-enamide directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for N-(1,3-dioxaindan-5-yl)-2-cyano-3-[4-(difluoromethoxy)phenyl]prop-2-enamide?
Yes, KEHONG BIO provides custom synthesis services for N-(1,3-dioxaindan-5-yl)-2-cyano-3-[4-(difluoromethoxy)phenyl]prop-2-enamide and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.