![2-cyano-3-[4-(difluoromethoxy)phenyl]-N-methyl-N-(1-methylpiperidin-4-yl)prop-2-enamide structure](/static/products/3261/326188-52-7.webp)
2-cyano-3-[4-(difluoromethoxy)phenyl]-N-methyl-N-(1-methylpiperidin-4-yl)prop-2-enamide
TL;DR: 2-cyano-3-[4-(difluoromethoxy)phenyl]-N-methyl-N-(1-methylpiperidin-4-yl)prop-2-enamide (CAS 326188-52-7) is a chemical compound with molecular formula C18H21F2N3O2 and molecular weight 349.16 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
(Z)-2-cyano-3-[4-(difluoromethoxy)phenyl]-N-methyl-N-(1-methylpiperidin-4-yl)prop-2-enamide
Also Known As: 2-cyano-3-[4-(difluoromethoxy)phenyl]-N-methyl-N-(1-methylpiperidin-4-yl)prop-2-enamide, (Z)-2-cyano-3-[4-(difluoromethoxy)phenyl]-N-methyl-N-(1-methylpiperidin-4-yl)prop-2-enamide
| Molecular Formula | C18H21F2N3O2 |
|---|---|
| Molecular Weight | 349.16 g/mol |
| LogP | 2.74758 |
| Topological Polar Surface Area | 56.57 Ų |
| Hydrogen Bond Donors | 0 |
| Hydrogen Bond Acceptors | 4 |
| Rotatable Bonds | 5 |
| Exact Mass | 349.1602 |
| Heavy Atoms | 25 |
| Complexity | 659.8939 |
Chemical Identifiers
| CAS Number | 326188-52-7 |
|---|---|
| SMILES | CN1CCC(CC1)N(C)C(=O)/C(=C\C2=CC=C(C=C2)OC(F)F)/C#N |
Product Overview
2-cyano-3-[4-(difluoromethoxy)phenyl]-N-methyl-N-(1-methylpiperidin-4-yl)prop-2-enamide (CAS 326188-52-7), with molecular formula C18H21F2N3O2 and molecular weight 349.16 g/mol. IUPAC: (Z)-2-cyano-3-[4-(difluoromethoxy)phenyl]-N-methyl-N-(1-methylpiperidin-4-yl)prop-2-enamide.
Chemical Property Profile of 2-cyano-3-[4-(difluoromethoxy)phenyl]-N-methyl-N-(1-methylpiperidin-4-yl)prop-2-enamide
Property Insights of 2-cyano-3-[4-(difluoromethoxy)phenyl]-N-methyl-N-(1-methylpiperidin-4-yl)prop-2-enamide
The XLogP value of 2.74758 suggests moderate lipophilicity, balancing water solubility and membrane permeability for 2-cyano-3-[4-(difluoromethoxy)phenyl]-N-methyl-N-(1-methylpiperidin-4-yl)prop-2-enamide. With a topological polar surface area (TPSA) of 56.57 Ų, 2-cyano-3-[4-(difluoromethoxy)phenyl]-N-methyl-N-(1-methylpiperidin-4-yl)prop-2-enamide exhibits relatively low polarity, potentially indicating favorable cell membrane permeability. Following Lipinski's Rule of Five, 2-cyano-3-[4-(difluoromethoxy)phenyl]-N-methyl-N-(1-methylpiperidin-4-yl)prop-2-enamide has 0 hydrogen bond donor(s) and 4 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of 2-cyano-3-[4-(difluoromethoxy)phenyl]-N-methyl-N-(1-methylpiperidin-4-yl)prop-2-enamide?
The CAS number of 2-cyano-3-[4-(difluoromethoxy)phenyl]-N-methyl-N-(1-methylpiperidin-4-yl)prop-2-enamide is 326188-52-7.
What is the molecular formula of 2-cyano-3-[4-(difluoromethoxy)phenyl]-N-methyl-N-(1-methylpiperidin-4-yl)prop-2-enamide?
The molecular formula of 2-cyano-3-[4-(difluoromethoxy)phenyl]-N-methyl-N-(1-methylpiperidin-4-yl)prop-2-enamide is C18H21F2N3O2.
What is the molecular weight of 2-cyano-3-[4-(difluoromethoxy)phenyl]-N-methyl-N-(1-methylpiperidin-4-yl)prop-2-enamide?
The molecular weight of 2-cyano-3-[4-(difluoromethoxy)phenyl]-N-methyl-N-(1-methylpiperidin-4-yl)prop-2-enamide is 349.16 g/mol.
Where can I buy 2-cyano-3-[4-(difluoromethoxy)phenyl]-N-methyl-N-(1-methylpiperidin-4-yl)prop-2-enamide?
You can request a quote for 2-cyano-3-[4-(difluoromethoxy)phenyl]-N-methyl-N-(1-methylpiperidin-4-yl)prop-2-enamide directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for 2-cyano-3-[4-(difluoromethoxy)phenyl]-N-methyl-N-(1-methylpiperidin-4-yl)prop-2-enamide?
Yes, KEHONG BIO provides custom synthesis services for 2-cyano-3-[4-(difluoromethoxy)phenyl]-N-methyl-N-(1-methylpiperidin-4-yl)prop-2-enamide and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.