![N-(5-bromopyridin-2-yl)-2-cyano-3-[4-(difluoromethoxy)phenyl]prop-2-enamide structure](/static/products/3261/326188-47-0.webp)
N-(5-bromopyridin-2-yl)-2-cyano-3-[4-(difluoromethoxy)phenyl]prop-2-enamide
TL;DR: N-(5-bromopyridin-2-yl)-2-cyano-3-[4-(difluoromethoxy)phenyl]prop-2-enamide (CAS 326188-47-0) is a chemical compound with molecular formula C16H10BrF2N3O2 and molecular weight 392.99 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
(E)-N-(5-bromo-2-pyridinyl)-2-cyano-3-[4-(difluoromethoxy)phenyl]prop-2-enamide
Also Known As: (E)-N-(5-bromopyridin-2-yl)-2-cyano-3-[4-(difluoromethoxy)phenyl]prop-2-enamide, N-(5-bromopyridin-2-yl)-2-cyano-3-[4-(difluoromethoxy)phenyl]prop-2-enamide
| Molecular Formula | C16H10BrF2N3O2 |
|---|---|
| Molecular Weight | 392.99 g/mol |
| LogP | 3.99118 |
| Topological Polar Surface Area | 75.01 Ų |
| Hydrogen Bond Donors | 1 |
| Hydrogen Bond Acceptors | 4 |
| Rotatable Bonds | 5 |
| Exact Mass | 392.99246 |
| Heavy Atoms | 24 |
| Complexity | 784.46497 |
Chemical Identifiers
| CAS Number | 326188-47-0 |
|---|---|
| SMILES | C1=CC(=CC=C1/C=C(\C#N)/C(=O)NC2=NC=C(C=C2)Br)OC(F)F |
Product Overview
N-(5-bromopyridin-2-yl)-2-cyano-3-[4-(difluoromethoxy)phenyl]prop-2-enamide (CAS 326188-47-0), with molecular formula C16H10BrF2N3O2 and molecular weight 392.99 g/mol. IUPAC: (E)-N-(5-bromo-2-pyridinyl)-2-cyano-3-[4-(difluoromethoxy)phenyl]prop-2-enamide.
Chemical Property Profile of N-(5-bromopyridin-2-yl)-2-cyano-3-[4-(difluoromethoxy)phenyl]prop-2-enamide
Property Insights of N-(5-bromopyridin-2-yl)-2-cyano-3-[4-(difluoromethoxy)phenyl]prop-2-enamide
The XLogP value of 3.99118 indicates that N-(5-bromopyridin-2-yl)-2-cyano-3-[4-(difluoromethoxy)phenyl]prop-2-enamide is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. The TPSA of 75.01 Ų falls within the moderate polarity range, balancing permeability and solubility for N-(5-bromopyridin-2-yl)-2-cyano-3-[4-(difluoromethoxy)phenyl]prop-2-enamide. Following Lipinski's Rule of Five, N-(5-bromopyridin-2-yl)-2-cyano-3-[4-(difluoromethoxy)phenyl]prop-2-enamide has 1 hydrogen bond donor(s) and 4 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of N-(5-bromopyridin-2-yl)-2-cyano-3-[4-(difluoromethoxy)phenyl]prop-2-enamide?
The CAS number of N-(5-bromopyridin-2-yl)-2-cyano-3-[4-(difluoromethoxy)phenyl]prop-2-enamide is 326188-47-0.
What is the molecular formula of N-(5-bromopyridin-2-yl)-2-cyano-3-[4-(difluoromethoxy)phenyl]prop-2-enamide?
The molecular formula of N-(5-bromopyridin-2-yl)-2-cyano-3-[4-(difluoromethoxy)phenyl]prop-2-enamide is C16H10BrF2N3O2.
What is the molecular weight of N-(5-bromopyridin-2-yl)-2-cyano-3-[4-(difluoromethoxy)phenyl]prop-2-enamide?
The molecular weight of N-(5-bromopyridin-2-yl)-2-cyano-3-[4-(difluoromethoxy)phenyl]prop-2-enamide is 392.99 g/mol.
Where can I buy N-(5-bromopyridin-2-yl)-2-cyano-3-[4-(difluoromethoxy)phenyl]prop-2-enamide?
You can request a quote for N-(5-bromopyridin-2-yl)-2-cyano-3-[4-(difluoromethoxy)phenyl]prop-2-enamide directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for N-(5-bromopyridin-2-yl)-2-cyano-3-[4-(difluoromethoxy)phenyl]prop-2-enamide?
Yes, KEHONG BIO provides custom synthesis services for N-(5-bromopyridin-2-yl)-2-cyano-3-[4-(difluoromethoxy)phenyl]prop-2-enamide and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.