AF-399/37112059
TL;DR: AF-399/37112059 (CAS 325854-84-0) is a chemical compound with molecular formula C26H24ClN3O3 and molecular weight 461.15 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
5-(2-chlorophenyl)-3-[4-(dimethylamino)phenyl]-2-(2-methylphenyl)-3a,6a-dihydro-3H-pyrrolo[3,4-d][1,2]oxazole-4,6-dione
Also Known As: AF-399/37112059, 5-(2-chlorophenyl)-3-[4-(dimethylamino)phenyl]-2-(2-methylphenyl)-hexahydro-2H-pyrrolo[3,4-d][1,2]oxazole-4,6-dione, F0270-0059, 5-(2-chlorophenyl)-3-(4-(dimethylamino)phenyl)-2-(o-tolyl)dihydro-2H-pyrrolo[3,4-d]isoxazole-4,6(5H,6aH)-dione, 5-(2-chlorophenyl)-3-[4-(dimethylamino)phenyl]-2-(2-methylphenyl)-3a,6a-dihydro-3H-pyrrolo[3,4-d][1,2]oxazole-4,6-dione
| Molecular Formula | C26H24ClN3O3 |
|---|---|
| Molecular Weight | 461.15 g/mol |
| LogP | 4.76552 |
| Topological Polar Surface Area | 53.09 Ų |
| Hydrogen Bond Donors | 0 |
| Hydrogen Bond Acceptors | 5 |
| Rotatable Bonds | 4 |
| Exact Mass | 461.1506 |
| Heavy Atoms | 33 |
| Complexity | 1227.4615 |
Chemical Identifiers
| CAS Number | 325854-84-0 |
|---|---|
| SMILES | CC1=CC=CC=C1N2C(C3C(O2)C(=O)N(C3=O)C4=CC=CC=C4Cl)C5=CC=C(C=C5)N(C)C |
Product Overview
AF-399/37112059 (CAS 325854-84-0), with molecular formula C26H24ClN3O3 and molecular weight 461.15 g/mol. IUPAC: 5-(2-chlorophenyl)-3-[4-(dimethylamino)phenyl]-2-(2-methylphenyl)-3a,6a-dihydro-3H-pyrrolo[3,4-d][1,2]oxazole-4,6-dione.
Chemical Property Profile of AF-399/37112059
Property Insights of AF-399/37112059
The XLogP value of 4.76552 indicates that AF-399/37112059 is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. With a topological polar surface area (TPSA) of 53.09 Ų, AF-399/37112059 exhibits relatively low polarity, potentially indicating favorable cell membrane permeability. Following Lipinski's Rule of Five, AF-399/37112059 has 0 hydrogen bond donor(s) and 5 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of AF-399/37112059?
The CAS number of AF-399/37112059 is 325854-84-0.
What is the molecular formula of AF-399/37112059?
The molecular formula of AF-399/37112059 is C26H24ClN3O3.
What is the molecular weight of AF-399/37112059?
The molecular weight of AF-399/37112059 is 461.15 g/mol.
Where can I buy AF-399/37112059?
You can request a quote for AF-399/37112059 directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for AF-399/37112059?
Yes, KEHONG BIO provides custom synthesis services for AF-399/37112059 and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.