1-(Thiophen-2-ylsulfonyl)-3-(trifluoromethyl)piperidine
TL;DR: 1-(Thiophen-2-ylsulfonyl)-3-(trifluoromethyl)piperidine (CAS 325702-34-9) is a chemical compound with molecular formula C10H12F3NO2S2 and molecular weight 299.03 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
1-thiophen-2-ylsulfonyl-3-(trifluoromethyl)piperidine
Also Known As: 1-(thiophen-2-ylsulfonyl)-3-(trifluoromethyl)piperidine, 1-thiophen-2-ylsulfonyl-3-(trifluoromethyl)piperidine, VU0494006-1, F0774-0104, AF-399/12856001
| Molecular Formula | C10H12F3NO2S2 |
|---|---|
| Molecular Weight | 299.03 g/mol |
| LogP | 2.7111 |
| Topological Polar Surface Area | 37.38 Ų |
| Hydrogen Bond Donors | 0 |
| Hydrogen Bond Acceptors | 3 |
| Rotatable Bonds | 2 |
| Exact Mass | 299.02615 |
| Heavy Atoms | 18 |
| Complexity | 495.6925 |
Chemical Identifiers
| CAS Number | 325702-34-9 |
|---|---|
| SMILES | C1CC(CN(C1)S(=O)(=O)C2=CC=CS2)C(F)(F)F |
Product Overview
1-(Thiophen-2-ylsulfonyl)-3-(trifluoromethyl)piperidine (CAS 325702-34-9), with molecular formula C10H12F3NO2S2 and molecular weight 299.03 g/mol. IUPAC: 1-thiophen-2-ylsulfonyl-3-(trifluoromethyl)piperidine.
Chemical Property Profile of 1-(Thiophen-2-ylsulfonyl)-3-(trifluoromethyl)piperidine
Property Insights of 1-(Thiophen-2-ylsulfonyl)-3-(trifluoromethyl)piperidine
The XLogP value of 2.7111 suggests moderate lipophilicity, balancing water solubility and membrane permeability for 1-(Thiophen-2-ylsulfonyl)-3-(trifluoromethyl)piperidine. With a topological polar surface area (TPSA) of 37.38 Ų, 1-(Thiophen-2-ylsulfonyl)-3-(trifluoromethyl)piperidine exhibits relatively low polarity, potentially indicating favorable cell membrane permeability. Following Lipinski's Rule of Five, 1-(Thiophen-2-ylsulfonyl)-3-(trifluoromethyl)piperidine has 0 hydrogen bond donor(s) and 3 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of 1-(Thiophen-2-ylsulfonyl)-3-(trifluoromethyl)piperidine?
The CAS number of 1-(Thiophen-2-ylsulfonyl)-3-(trifluoromethyl)piperidine is 325702-34-9.
What is the molecular formula of 1-(Thiophen-2-ylsulfonyl)-3-(trifluoromethyl)piperidine?
The molecular formula of 1-(Thiophen-2-ylsulfonyl)-3-(trifluoromethyl)piperidine is C10H12F3NO2S2.
What is the molecular weight of 1-(Thiophen-2-ylsulfonyl)-3-(trifluoromethyl)piperidine?
The molecular weight of 1-(Thiophen-2-ylsulfonyl)-3-(trifluoromethyl)piperidine is 299.03 g/mol.
Where can I buy 1-(Thiophen-2-ylsulfonyl)-3-(trifluoromethyl)piperidine?
You can request a quote for 1-(Thiophen-2-ylsulfonyl)-3-(trifluoromethyl)piperidine directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for 1-(Thiophen-2-ylsulfonyl)-3-(trifluoromethyl)piperidine?
Yes, KEHONG BIO provides custom synthesis services for 1-(Thiophen-2-ylsulfonyl)-3-(trifluoromethyl)piperidine and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.