(E)-N-(4-(3-(4-chlorophenyl)acryloyl)phenyl)nicotinamide
TL;DR: (E)-N-(4-(3-(4-chlorophenyl)acryloyl)phenyl)nicotinamide (CAS 325700-27-4) is a chemical compound with molecular formula C21H15ClN2O2 and molecular weight 362.08 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
N-[4-[(E)-3-(4-chlorophenyl)prop-2-enoyl]phenyl]pyridine-3-carboxamide
Also Known As: BIM-0042045.P001, F0855-0040, (E)-N-(4-(3-(4-chlorophenyl)acryloyl)phenyl)nicotinamide, N-(4-(3-(4-Chlorophenyl)acryloyl)phenyl)nicotinamide, N-{4-[(2E)-3-(4-CHLOROPHENYL)PROP-2-ENOYL]PHENYL}PYRIDINE-3-CARBOXAMIDE
| Molecular Formula | C21H15ClN2O2 |
|---|---|
| Molecular Weight | 362.08 g/mol |
| LogP | 4.8834 |
| Topological Polar Surface Area | 59.06 Ų |
| Hydrogen Bond Donors | 1 |
| Hydrogen Bond Acceptors | 3 |
| Rotatable Bonds | 5 |
| Exact Mass | 362.0822 |
| Heavy Atoms | 26 |
| Complexity | 934.0098 |
Chemical Identifiers
| CAS Number | 325700-27-4 |
|---|---|
| SMILES | C1=CC(=CN=C1)C(=O)NC2=CC=C(C=C2)C(=O)/C=C/C3=CC=C(C=C3)Cl |
Product Overview
(E)-N-(4-(3-(4-chlorophenyl)acryloyl)phenyl)nicotinamide (CAS 325700-27-4), with molecular formula C21H15ClN2O2 and molecular weight 362.08 g/mol. IUPAC: N-[4-[(E)-3-(4-chlorophenyl)prop-2-enoyl]phenyl]pyridine-3-carboxamide.
Chemical Property Profile of (E)-N-(4-(3-(4-chlorophenyl)acryloyl)phenyl)nicotinamide
Property Insights of (E)-N-(4-(3-(4-chlorophenyl)acryloyl)phenyl)nicotinamide
The XLogP value of 4.8834 indicates that (E)-N-(4-(3-(4-chlorophenyl)acryloyl)phenyl)nicotinamide is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. With a topological polar surface area (TPSA) of 59.06 Ų, (E)-N-(4-(3-(4-chlorophenyl)acryloyl)phenyl)nicotinamide exhibits relatively low polarity, potentially indicating favorable cell membrane permeability. Following Lipinski's Rule of Five, (E)-N-(4-(3-(4-chlorophenyl)acryloyl)phenyl)nicotinamide has 1 hydrogen bond donor(s) and 3 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of (E)-N-(4-(3-(4-chlorophenyl)acryloyl)phenyl)nicotinamide?
The CAS number of (E)-N-(4-(3-(4-chlorophenyl)acryloyl)phenyl)nicotinamide is 325700-27-4.
What is the molecular formula of (E)-N-(4-(3-(4-chlorophenyl)acryloyl)phenyl)nicotinamide?
The molecular formula of (E)-N-(4-(3-(4-chlorophenyl)acryloyl)phenyl)nicotinamide is C21H15ClN2O2.
What is the molecular weight of (E)-N-(4-(3-(4-chlorophenyl)acryloyl)phenyl)nicotinamide?
The molecular weight of (E)-N-(4-(3-(4-chlorophenyl)acryloyl)phenyl)nicotinamide is 362.08 g/mol.
Where can I buy (E)-N-(4-(3-(4-chlorophenyl)acryloyl)phenyl)nicotinamide?
You can request a quote for (E)-N-(4-(3-(4-chlorophenyl)acryloyl)phenyl)nicotinamide directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for (E)-N-(4-(3-(4-chlorophenyl)acryloyl)phenyl)nicotinamide?
Yes, KEHONG BIO provides custom synthesis services for (E)-N-(4-(3-(4-chlorophenyl)acryloyl)phenyl)nicotinamide and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.