methyl}quinolin-8-ol structure](/static/products/3254/325474-51-9.webp)
7-{[4-(Difluoromethoxy)phenyl](2-pyridylamino)methyl}quinolin-8-ol
TL;DR: 7-{[4-(Difluoromethoxy)phenyl](2-pyridylamino)methyl}quinolin-8-ol (CAS 325474-51-9) is a chemical compound with molecular formula C22H17F2N3O2 and molecular weight 393.13 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
7-[[4-(difluoromethoxy)phenyl]-(pyridin-2-ylamino)methyl]quinolin-8-ol
Also Known As: AF-399/13275007, 7-{[4-(difluoromethoxy)phenyl](2-pyridylamino)methyl}quinolin-8-ol, 7-{[4-(difluoromethoxy)phenyl](pyridin-2-ylamino)methyl}quinolin-8-ol, 7-[[4-(difluoromethoxy)phenyl]-(pyridin-2-ylamino)methyl]quinolin-8-ol, 7-[[4-(difluoromethoxy)phenyl](2-pyridinylamino)methyl]-8-quinolinol
| Molecular Formula | C22H17F2N3O2 |
|---|---|
| Molecular Weight | 393.13 g/mol |
| LogP | 5.1383 |
| Topological Polar Surface Area | 67.27 Ų |
| Hydrogen Bond Donors | 2 |
| Hydrogen Bond Acceptors | 5 |
| Rotatable Bonds | 6 |
| Exact Mass | 393.12888 |
| Heavy Atoms | 29 |
| Complexity | 1106.0261 |
Chemical Identifiers
| CAS Number | 325474-51-9 |
|---|---|
| SMILES | C1=CC=NC(=C1)NC(C2=CC=C(C=C2)OC(F)F)C3=C(C4=C(C=CC=N4)C=C3)O |
Product Overview
7-{[4-(Difluoromethoxy)phenyl](2-pyridylamino)methyl}quinolin-8-ol (CAS 325474-51-9), with molecular formula C22H17F2N3O2 and molecular weight 393.13 g/mol. IUPAC: 7-[[4-(difluoromethoxy)phenyl]-(pyridin-2-ylamino)methyl]quinolin-8-ol.
Chemical Property Profile of 7-{[4-(Difluoromethoxy)phenyl](2-pyridylamino)methyl}quinolin-8-ol
Property Insights of 7-{[4-(Difluoromethoxy)phenyl](2-pyridylamino)methyl}quinolin-8-ol
The XLogP value of 5.1383 indicates that 7-{[4-(Difluoromethoxy)phenyl](2-pyridylamino)methyl}quinolin-8-ol is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. The TPSA of 67.27 Ų falls within the moderate polarity range, balancing permeability and solubility for 7-{[4-(Difluoromethoxy)phenyl](2-pyridylamino)methyl}quinolin-8-ol. Following Lipinski's Rule of Five, 7-{[4-(Difluoromethoxy)phenyl](2-pyridylamino)methyl}quinolin-8-ol has 2 hydrogen bond donor(s) and 5 hydrogen bond acceptor(s), which may warrant consideration for formulation optimization.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of 7-{[4-(Difluoromethoxy)phenyl](2-pyridylamino)methyl}quinolin-8-ol?
The CAS number of 7-{[4-(Difluoromethoxy)phenyl](2-pyridylamino)methyl}quinolin-8-ol is 325474-51-9.
What is the molecular formula of 7-{[4-(Difluoromethoxy)phenyl](2-pyridylamino)methyl}quinolin-8-ol?
The molecular formula of 7-{[4-(Difluoromethoxy)phenyl](2-pyridylamino)methyl}quinolin-8-ol is C22H17F2N3O2.
What is the molecular weight of 7-{[4-(Difluoromethoxy)phenyl](2-pyridylamino)methyl}quinolin-8-ol?
The molecular weight of 7-{[4-(Difluoromethoxy)phenyl](2-pyridylamino)methyl}quinolin-8-ol is 393.13 g/mol.
Where can I buy 7-{[4-(Difluoromethoxy)phenyl](2-pyridylamino)methyl}quinolin-8-ol?
You can request a quote for 7-{[4-(Difluoromethoxy)phenyl](2-pyridylamino)methyl}quinolin-8-ol directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for 7-{[4-(Difluoromethoxy)phenyl](2-pyridylamino)methyl}quinolin-8-ol?
Yes, KEHONG BIO provides custom synthesis services for 7-{[4-(Difluoromethoxy)phenyl](2-pyridylamino)methyl}quinolin-8-ol and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.