3-(4-Fluorophenyl)-3-(8-quinolylthio)-1-(2-thienyl)propan-1-one
TL;DR: 3-(4-Fluorophenyl)-3-(8-quinolylthio)-1-(2-thienyl)propan-1-one (CAS 325474-33-7) is a chemical compound with molecular formula C22H16FNOS2 and molecular weight 393.07 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
3-(4-fluorophenyl)-3-quinolin-8-ylsulfanyl-1-thiophen-2-ylpropan-1-one
Also Known As: VU0652392-1, AF-399/12854087, 3-(4-fluorophenyl)-3-(8-quinolylthio)-1-(2-thienyl)propan-1-one, F0472-0182, 3-(4-fluorophenyl)-3-(8-quinolinylsulfanyl)-1-(2-thienyl)-1-propanone
| Molecular Formula | C22H16FNOS2 |
|---|---|
| Molecular Weight | 393.07 g/mol |
| LogP | 6.5418 |
| Topological Polar Surface Area | 29.96 Ų |
| Hydrogen Bond Donors | 0 |
| Hydrogen Bond Acceptors | 4 |
| Rotatable Bonds | 6 |
| Exact Mass | 393.06573 |
| Heavy Atoms | 27 |
| Complexity | 1056.0826 |
Chemical Identifiers
| CAS Number | 325474-33-7 |
|---|---|
| SMILES | C1=CC2=C(C(=C1)SC(CC(=O)C3=CC=CS3)C4=CC=C(C=C4)F)N=CC=C2 |
Product Overview
3-(4-Fluorophenyl)-3-(8-quinolylthio)-1-(2-thienyl)propan-1-one (CAS 325474-33-7), with molecular formula C22H16FNOS2 and molecular weight 393.07 g/mol. IUPAC: 3-(4-fluorophenyl)-3-quinolin-8-ylsulfanyl-1-thiophen-2-ylpropan-1-one.
Chemical Property Profile of 3-(4-Fluorophenyl)-3-(8-quinolylthio)-1-(2-thienyl)propan-1-one
Property Insights of 3-(4-Fluorophenyl)-3-(8-quinolylthio)-1-(2-thienyl)propan-1-one
The XLogP value of 6.5418 indicates that 3-(4-Fluorophenyl)-3-(8-quinolylthio)-1-(2-thienyl)propan-1-one is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. With a topological polar surface area (TPSA) of 29.96 Ų, 3-(4-Fluorophenyl)-3-(8-quinolylthio)-1-(2-thienyl)propan-1-one exhibits relatively low polarity, potentially indicating favorable cell membrane permeability. Following Lipinski's Rule of Five, 3-(4-Fluorophenyl)-3-(8-quinolylthio)-1-(2-thienyl)propan-1-one has 0 hydrogen bond donor(s) and 4 hydrogen bond acceptor(s), which may warrant consideration for formulation optimization.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of 3-(4-Fluorophenyl)-3-(8-quinolylthio)-1-(2-thienyl)propan-1-one?
The CAS number of 3-(4-Fluorophenyl)-3-(8-quinolylthio)-1-(2-thienyl)propan-1-one is 325474-33-7.
What is the molecular formula of 3-(4-Fluorophenyl)-3-(8-quinolylthio)-1-(2-thienyl)propan-1-one?
The molecular formula of 3-(4-Fluorophenyl)-3-(8-quinolylthio)-1-(2-thienyl)propan-1-one is C22H16FNOS2.
What is the molecular weight of 3-(4-Fluorophenyl)-3-(8-quinolylthio)-1-(2-thienyl)propan-1-one?
The molecular weight of 3-(4-Fluorophenyl)-3-(8-quinolylthio)-1-(2-thienyl)propan-1-one is 393.07 g/mol.
Where can I buy 3-(4-Fluorophenyl)-3-(8-quinolylthio)-1-(2-thienyl)propan-1-one?
You can request a quote for 3-(4-Fluorophenyl)-3-(8-quinolylthio)-1-(2-thienyl)propan-1-one directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for 3-(4-Fluorophenyl)-3-(8-quinolylthio)-1-(2-thienyl)propan-1-one?
Yes, KEHONG BIO provides custom synthesis services for 3-(4-Fluorophenyl)-3-(8-quinolylthio)-1-(2-thienyl)propan-1-one and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.