1-(5-bromo-1H-indol-3-yl)-2,2,2-trifluoroethanone
TL;DR: 1-(5-bromo-1H-indol-3-yl)-2,2,2-trifluoroethanone (CAS 32387-18-1) is a chemical compound with molecular formula C10H5BrF3NO and molecular weight 290.95 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
1-(5-bromo-1H-indol-3-yl)-2,2,2-trifluoroethanone
Also Known As: 5-Bromo-3-(trifluoroacetyl)indole, 1-(5-bromo-1H-indol-3-yl)-2,2,2-trifluoroethanone, 1-acetyl-5-bromo-indole, 5-Bromo-1H-indole-3-trimethyl ethanone, 6341AJ
| Molecular Formula | C10H5BrF3NO |
|---|---|
| Molecular Weight | 290.95 g/mol |
| LogP | 3.6754 |
| Topological Polar Surface Area | 32.86 Ų |
| Hydrogen Bond Donors | 1 |
| Hydrogen Bond Acceptors | 1 |
| Rotatable Bonds | 1 |
| Exact Mass | 290.95065 |
| Heavy Atoms | 16 |
| Complexity | 558.67975 |
Chemical Identifiers
| CAS Number | 32387-18-1 |
|---|---|
| SMILES | C1=CC2=C(C=C1Br)C(=CN2)C(=O)C(F)(F)F |
Product Overview
1-(5-bromo-1H-indol-3-yl)-2,2,2-trifluoroethanone (CAS 32387-18-1), with molecular formula C10H5BrF3NO and molecular weight 290.95 g/mol. IUPAC: 1-(5-bromo-1H-indol-3-yl)-2,2,2-trifluoroethanone.
Chemical Property Profile of 1-(5-bromo-1H-indol-3-yl)-2,2,2-trifluoroethanone
Property Insights of 1-(5-bromo-1H-indol-3-yl)-2,2,2-trifluoroethanone
The XLogP value of 3.6754 indicates that 1-(5-bromo-1H-indol-3-yl)-2,2,2-trifluoroethanone is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. With a topological polar surface area (TPSA) of 32.86 Ų, 1-(5-bromo-1H-indol-3-yl)-2,2,2-trifluoroethanone exhibits relatively low polarity, potentially indicating favorable cell membrane permeability. Following Lipinski's Rule of Five, 1-(5-bromo-1H-indol-3-yl)-2,2,2-trifluoroethanone has 1 hydrogen bond donor(s) and 1 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of 1-(5-bromo-1H-indol-3-yl)-2,2,2-trifluoroethanone?
The CAS number of 1-(5-bromo-1H-indol-3-yl)-2,2,2-trifluoroethanone is 32387-18-1.
What is the molecular formula of 1-(5-bromo-1H-indol-3-yl)-2,2,2-trifluoroethanone?
The molecular formula of 1-(5-bromo-1H-indol-3-yl)-2,2,2-trifluoroethanone is C10H5BrF3NO.
What is the molecular weight of 1-(5-bromo-1H-indol-3-yl)-2,2,2-trifluoroethanone?
The molecular weight of 1-(5-bromo-1H-indol-3-yl)-2,2,2-trifluoroethanone is 290.95 g/mol.
Where can I buy 1-(5-bromo-1H-indol-3-yl)-2,2,2-trifluoroethanone?
You can request a quote for 1-(5-bromo-1H-indol-3-yl)-2,2,2-trifluoroethanone directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for 1-(5-bromo-1H-indol-3-yl)-2,2,2-trifluoroethanone?
Yes, KEHONG BIO provides custom synthesis services for 1-(5-bromo-1H-indol-3-yl)-2,2,2-trifluoroethanone and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.