LY 43578
TL;DR: LY 43578 (CAS 32296-86-9) is a chemical compound with molecular formula C17H12Cl2N2O and molecular weight 330.03 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
bis(4-chlorophenyl)-pyrimidin-5-ylmethanol
Also Known As: Bis(4-chlorophenyl)(5-pyrimidinyl)methanol, bis(4-chlorophenyl)-pyrimidin-5-ylmethanol, BIS(4-CHLOROPHENYL)(PYRIMIDIN-5-YL)METHANOL, 5-Pyrimidinemethanol, a,a-bis(4-chlorophenyl)-, NCI60_008514
| Molecular Formula | C17H12Cl2N2O |
|---|---|
| Molecular Weight | 330.03 g/mol |
| LogP | 3.8 |
| Topological Polar Surface Area | 46.0 Ų |
| Hydrogen Bond Donors | 1 |
| Hydrogen Bond Acceptors | 3 |
| Rotatable Bonds | 3 |
| Exact Mass | 330.03265 |
| Heavy Atoms | 22 |
| Complexity | 325.0 |
Chemical Identifiers
| CAS Number | 32296-86-9 |
|---|---|
| SMILES | C1=CC(=CC=C1C(C2=CC=C(C=C2)Cl)(C3=CN=CN=C3)O)Cl |
| InChIKey | CSRYTZCLFTYZLS-UHFFFAOYSA-N |
Patent-Derived Application Labels
Derived from 2 IPC patent classification(s) across the SureChEMBL global patent database.
Product Overview
LY 43578 (CAS 32296-86-9), with molecular formula C17H12Cl2N2O and molecular weight 330.03 g/mol. IUPAC: bis(4-chlorophenyl)-pyrimidin-5-ylmethanol.
Chemical Property Profile of LY 43578
Property Insights of LY 43578
The XLogP value of 3.8 indicates that LY 43578 is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. With a topological polar surface area (TPSA) of 46.0 Ų, LY 43578 exhibits relatively low polarity, potentially indicating favorable cell membrane permeability. Following Lipinski's Rule of Five, LY 43578 has 1 hydrogen bond donor(s) and 3 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of LY 43578?
The CAS number of LY 43578 is 32296-86-9.
What is the molecular formula of LY 43578?
The molecular formula of LY 43578 is C17H12Cl2N2O.
What is the molecular weight of LY 43578?
The molecular weight of LY 43578 is 330.03 g/mol.
Where can I buy LY 43578?
You can request a quote for LY 43578 directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for LY 43578?
Yes, KEHONG BIO provides custom synthesis services for LY 43578 and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.