4-Chloro-6-(4-methylpiperazin-1-yl)pyrimidin-2-amine
TL;DR: 4-Chloro-6-(4-methylpiperazin-1-yl)pyrimidin-2-amine (CAS 322691-38-3) is a chemical compound with molecular formula C9H14ClN5 and molecular weight 227.09 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
4-chloro-6-(4-methylpiperazin-1-yl)pyrimidin-2-amine
Also Known As: 4-chloro-6-(4-methylpiperazin-1-yl)pyrimidin-2-amine, Bionet2_000912, 4-chloro-6-(4-methyl-1-piperazinyl)-2-pyrimidinamine, 4CH-019279, BB 0259610
| Molecular Formula | C9H14ClN5 |
|---|---|
| Molecular Weight | 227.09 g/mol |
| LogP | 0.464 |
| Topological Polar Surface Area | 58.28 Ų |
| Hydrogen Bond Donors | 1 |
| Hydrogen Bond Acceptors | 5 |
| Rotatable Bonds | 1 |
| Exact Mass | 227.09378 |
| Heavy Atoms | 15 |
| Complexity | 328.106 |
Chemical Identifiers
| CAS Number | 322691-38-3 |
|---|---|
| SMILES | CN1CCN(CC1)C2=CC(=NC(=N2)N)Cl |
Product Overview
4-Chloro-6-(4-methylpiperazin-1-yl)pyrimidin-2-amine (CAS 322691-38-3), with molecular formula C9H14ClN5 and molecular weight 227.09 g/mol. IUPAC: 4-chloro-6-(4-methylpiperazin-1-yl)pyrimidin-2-amine.
Chemical Property Profile of 4-Chloro-6-(4-methylpiperazin-1-yl)pyrimidin-2-amine
Property Insights of 4-Chloro-6-(4-methylpiperazin-1-yl)pyrimidin-2-amine
The XLogP value of 0.464 suggests moderate lipophilicity, balancing water solubility and membrane permeability for 4-Chloro-6-(4-methylpiperazin-1-yl)pyrimidin-2-amine. With a topological polar surface area (TPSA) of 58.28 Ų, 4-Chloro-6-(4-methylpiperazin-1-yl)pyrimidin-2-amine exhibits relatively low polarity, potentially indicating favorable cell membrane permeability. Following Lipinski's Rule of Five, 4-Chloro-6-(4-methylpiperazin-1-yl)pyrimidin-2-amine has 1 hydrogen bond donor(s) and 5 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of 4-Chloro-6-(4-methylpiperazin-1-yl)pyrimidin-2-amine?
The CAS number of 4-Chloro-6-(4-methylpiperazin-1-yl)pyrimidin-2-amine is 322691-38-3.
What is the molecular formula of 4-Chloro-6-(4-methylpiperazin-1-yl)pyrimidin-2-amine?
The molecular formula of 4-Chloro-6-(4-methylpiperazin-1-yl)pyrimidin-2-amine is C9H14ClN5.
What is the molecular weight of 4-Chloro-6-(4-methylpiperazin-1-yl)pyrimidin-2-amine?
The molecular weight of 4-Chloro-6-(4-methylpiperazin-1-yl)pyrimidin-2-amine is 227.09 g/mol.
Where can I buy 4-Chloro-6-(4-methylpiperazin-1-yl)pyrimidin-2-amine?
You can request a quote for 4-Chloro-6-(4-methylpiperazin-1-yl)pyrimidin-2-amine directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for 4-Chloro-6-(4-methylpiperazin-1-yl)pyrimidin-2-amine?
Yes, KEHONG BIO provides custom synthesis services for 4-Chloro-6-(4-methylpiperazin-1-yl)pyrimidin-2-amine and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.