8L-943 structure

8L-943

TL;DR: 8L-943 (CAS 321998-80-5) is a chemical compound with molecular formula C19H16ClF3N4O5 and molecular weight 472.08 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.

10-[2-[[3-chloro-5-(trifluoromethyl)-2-pyridinyl]amino]ethyl]-9,11-dioxo-3-oxa-4,10-diazatetracyclo[5.5.1.02,6.08,12]tridec-4-ene-5-carboxylic acid

Also Known As: 8L-943, 10-(2-{[3-chloro-5-(trifluoromethyl)-2-pyridinyl]amino}ethyl)-9,11-dioxo-3-oxa-4,10-diazatetracyclo[5.5.1.0~2,6~.0~8,12~]tridec-4-ene-5-carboxylic acid, 10-(2-{[3-chloro-5-(trifluoromethyl)pyridin-2-yl]amino}ethyl)-9,11-dioxo-3-oxa-4,10-diazatetracyclo[5.5.1.0^{2,6}.0^{8,12}]tridec-4-ene-5-carboxylic acid, 10-[2-[[3-chloro-5-(trifluoromethyl)pyridin-2-yl]amino]ethyl]-9,11-dioxo-3-oxa-4,10-diazatetracyclo[5.5.1.02,6.08,12]tridec-4-ene-5-carboxylic acid, 10-(2-([3-CHLORO-5-(TRIFLUOROMETHYL)-2-PYRIDINYL]AMINO)ETHYL)-9,11-DIOXO-3-OXA-4,10-DIAZATETRACYCLO[5.5.1.0(2,6).0(8,12)]TRIDEC-4-ENE-5-CARBOXYLIC ACID

CAS: 321998-80-5
Molecular Formula C19H16ClF3N4O5
Molecular Weight 472.08 g/mol
LogP 1.8722
Topological Polar Surface Area 121.19 Ų
Hydrogen Bond Donors 2
Hydrogen Bond Acceptors 7
Rotatable Bonds 5
Exact Mass 472.07614
Heavy Atoms 32
Complexity 1063.889

Chemical Identifiers

CAS Number 321998-80-5
SMILES C1C2C3C(C1C4C2C(=NO4)C(=O)O)C(=O)N(C3=O)CCNC5=C(C=C(C=N5)C(F)(F)F)Cl

Product Overview

8L-943 (CAS 321998-80-5), with molecular formula C19H16ClF3N4O5 and molecular weight 472.08 g/mol. IUPAC: 10-[2-[[3-chloro-5-(trifluoromethyl)-2-pyridinyl]amino]ethyl]-9,11-dioxo-3-oxa-4,10-diazatetracyclo[5.5.1.02,6.08,12]tridec-4-ene-5-carboxylic acid.

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Safety Data Sheet (MSDS / SDS) View the Laboratory Chemical Safety Summary (LCSS) on PubChem — includes GHS classifications, hazard statements, first aid measures, and handling precautions.
View MSDS →

Chemical Property Profile of 8L-943

XLogP
1.8722
TPSA (Topological Polar Surface Area)
121.19
Hydrogen Bond Donors
2
Hydrogen Bond Acceptors
7
Rotatable Bonds
5
Heavy Atoms
32
Complexity
1063.889
Exact Mass
472.07614
Monoisotopic Mass
472.07614
Data Source: Chemical property values are referenced from PubChem, the world's largest open chemistry database maintained by the National Center for Biotechnology Information (NCBI), U.S. National Library of Medicine.

Property Insights of 8L-943

The XLogP value of 1.8722 suggests moderate lipophilicity, balancing water solubility and membrane permeability for 8L-943. The TPSA of 121.19 Ų falls within the moderate polarity range, balancing permeability and solubility for 8L-943. Following Lipinski's Rule of Five, 8L-943 has 2 hydrogen bond donor(s) and 7 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.

Frequently Asked Questions

What is the typical lead time for this product?
Lead time typically ranges from 3-7 business days for in-stock items. For larger quantities or custom orders, please contact us for specific lead times.
Can you provide samples for testing?
Yes, we offer sample quantities for quality testing. Please submit an inquiry with your requirements and we will arrange samples accordingly.
What documentation do you provide with the product?
We provide COA (Certificate of Analysis), MSDS (Material Safety Data Sheet), and technical data sheets with each shipment.
Do you ship internationally?
Yes, we ship to most countries worldwide. Shipping costs and delivery times vary by location. Please contact us for specific shipping information.

Frequently Asked Questions

What is the CAS number of 8L-943?

The CAS number of 8L-943 is 321998-80-5.

What is the molecular formula of 8L-943?

The molecular formula of 8L-943 is C19H16ClF3N4O5.

What is the molecular weight of 8L-943?

The molecular weight of 8L-943 is 472.08 g/mol.

Where can I buy 8L-943?

You can request a quote for 8L-943 directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.

Does KEHONG BIO offer custom synthesis for 8L-943?

Yes, KEHONG BIO provides custom synthesis services for 8L-943 and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.

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