8L-731
TL;DR: 8L-731 (CAS 321998-73-6) is a chemical compound with molecular formula C21H19Cl4N3 and molecular weight 453.03 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
1-[(2,6-dichlorophenyl)methyl]-4-[3-(2,4-dichlorophenyl)-1H-pyrazol-5-yl]piperidine
Also Known As: 8L-731, 4-[5-(2,4-dichlorophenyl)-1H-pyrazol-3-yl]-1-[(2,6-dichlorophenyl)methyl]piperidine, 1-[(2,6-dichlorophenyl)methyl]-4-[3-(2,4-dichlorophenyl)-1H-pyrazol-5-yl]piperidine, 1-(2,6-dichlorobenzyl)-4-[5-(2,4-dichlorophenyl)-1H-pyrazol-3-yl]piperidine, 1-[(2,6-dichlorophenyl)methyl]-4-[5-(2,4-dichlorophenyl)-2H-pyrazol-3-yl]piperidine
| Molecular Formula | C21H19Cl4N3 |
|---|---|
| Molecular Weight | 453.03 g/mol |
| LogP | 7.0699 |
| Topological Polar Surface Area | 31.92 Ų |
| Hydrogen Bond Donors | 1 |
| Hydrogen Bond Acceptors | 2 |
| Rotatable Bonds | 4 |
| Exact Mass | 453.0333 |
| Heavy Atoms | 28 |
| Complexity | 957.2821 |
Chemical Identifiers
| CAS Number | 321998-73-6 |
|---|---|
| SMILES | C1CN(CCC1C2=CC(=NN2)C3=C(C=C(C=C3)Cl)Cl)CC4=C(C=CC=C4Cl)Cl |
Product Overview
8L-731 (CAS 321998-73-6), with molecular formula C21H19Cl4N3 and molecular weight 453.03 g/mol. IUPAC: 1-[(2,6-dichlorophenyl)methyl]-4-[3-(2,4-dichlorophenyl)-1H-pyrazol-5-yl]piperidine.
Chemical Property Profile of 8L-731
Property Insights of 8L-731
The XLogP value of 7.0699 indicates that 8L-731 is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. With a topological polar surface area (TPSA) of 31.92 Ų, 8L-731 exhibits relatively low polarity, potentially indicating favorable cell membrane permeability. Following Lipinski's Rule of Five, 8L-731 has 1 hydrogen bond donor(s) and 2 hydrogen bond acceptor(s), which may warrant consideration for formulation optimization.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of 8L-731?
The CAS number of 8L-731 is 321998-73-6.
What is the molecular formula of 8L-731?
The molecular formula of 8L-731 is C21H19Cl4N3.
What is the molecular weight of 8L-731?
The molecular weight of 8L-731 is 453.03 g/mol.
Where can I buy 8L-731?
You can request a quote for 8L-731 directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for 8L-731?
Yes, KEHONG BIO provides custom synthesis services for 8L-731 and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.