N-((2-(difluoromethoxy)phenyl)carbamoyl)-2,2,2-trifluoroacetamide
TL;DR: N-((2-(difluoromethoxy)phenyl)carbamoyl)-2,2,2-trifluoroacetamide (CAS 321944-49-4) is a chemical compound with molecular formula C10H7F5N2O3 and molecular weight 298.04 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
N-[[2-(difluoromethoxy)phenyl]carbamoyl]-2,2,2-trifluoroacetamide
Also Known As: 1-[2-(difluoromethoxy)phenyl]-3-(2,2,2-trifluoroacetyl)urea, F0188-0023, N-((2-(difluoromethoxy)phenyl)carbamoyl)-2,2,2-trifluoroacetamide, N-[[2-(difluoromethoxy)phenyl]carbamoyl]-2,2,2-trifluoroacetamide, 1-[3-(o-difluoromethoxyphenyl)ureido]-2,2,2-trifluoro-1-ethanone
| Molecular Formula | C10H7F5N2O3 |
|---|---|
| Molecular Weight | 298.04 g/mol |
| LogP | 3.3 |
| Topological Polar Surface Area | 67.4 Ų |
| Hydrogen Bond Donors | 2 |
| Hydrogen Bond Acceptors | 8 |
| Rotatable Bonds | 3 |
| Exact Mass | 298.0377 |
| Heavy Atoms | 20 |
| Complexity | 361.0 |
Chemical Identifiers
| CAS Number | 321944-49-4 |
|---|---|
| SMILES | C1=CC=C(C(=C1)NC(=O)NC(=O)C(F)(F)F)OC(F)F |
| InChIKey | UYLVXXQCYBKKGO-UHFFFAOYSA-N |
Product Overview
N-((2-(difluoromethoxy)phenyl)carbamoyl)-2,2,2-trifluoroacetamide (CAS 321944-49-4), with molecular formula C10H7F5N2O3 and molecular weight 298.04 g/mol. IUPAC: N-[[2-(difluoromethoxy)phenyl]carbamoyl]-2,2,2-trifluoroacetamide.
Chemical Property Profile of N-((2-(difluoromethoxy)phenyl)carbamoyl)-2,2,2-trifluoroacetamide
Property Insights of N-((2-(difluoromethoxy)phenyl)carbamoyl)-2,2,2-trifluoroacetamide
The XLogP value of 3.3 indicates that N-((2-(difluoromethoxy)phenyl)carbamoyl)-2,2,2-trifluoroacetamide is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. The TPSA of 67.4 Ų falls within the moderate polarity range, balancing permeability and solubility for N-((2-(difluoromethoxy)phenyl)carbamoyl)-2,2,2-trifluoroacetamide. Following Lipinski's Rule of Five, N-((2-(difluoromethoxy)phenyl)carbamoyl)-2,2,2-trifluoroacetamide has 2 hydrogen bond donor(s) and 8 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of N-((2-(difluoromethoxy)phenyl)carbamoyl)-2,2,2-trifluoroacetamide?
The CAS number of N-((2-(difluoromethoxy)phenyl)carbamoyl)-2,2,2-trifluoroacetamide is 321944-49-4.
What is the molecular formula of N-((2-(difluoromethoxy)phenyl)carbamoyl)-2,2,2-trifluoroacetamide?
The molecular formula of N-((2-(difluoromethoxy)phenyl)carbamoyl)-2,2,2-trifluoroacetamide is C10H7F5N2O3.
What is the molecular weight of N-((2-(difluoromethoxy)phenyl)carbamoyl)-2,2,2-trifluoroacetamide?
The molecular weight of N-((2-(difluoromethoxy)phenyl)carbamoyl)-2,2,2-trifluoroacetamide is 298.04 g/mol.
Where can I buy N-((2-(difluoromethoxy)phenyl)carbamoyl)-2,2,2-trifluoroacetamide?
You can request a quote for N-((2-(difluoromethoxy)phenyl)carbamoyl)-2,2,2-trifluoroacetamide directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for N-((2-(difluoromethoxy)phenyl)carbamoyl)-2,2,2-trifluoroacetamide?
Yes, KEHONG BIO provides custom synthesis services for N-((2-(difluoromethoxy)phenyl)carbamoyl)-2,2,2-trifluoroacetamide and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.