9L-728
TL;DR: 9L-728 (CAS 321848-27-5) is a chemical compound with molecular formula C20H17Cl2F3N4 and molecular weight 440.08 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
3-chloro-2-[4-[3-(4-chlorophenyl)-1H-pyrazol-5-yl]piperidin-1-yl]-5-(trifluoromethyl)pyridine
Also Known As: 9L-728, 3-chloro-2-{4-[3-(4-chlorophenyl)-1H-pyrazol-5-yl]piperidin-1-yl}-5-(trifluoromethyl)pyridine, 3-chloro-2-[4-[3-(4-chlorophenyl)-1H-pyrazol-5-yl]piperidin-1-yl]-5-(trifluoromethyl)pyridine, 3-chloro-2-{4-[3-(4-chlorophenyl)-1H-pyrazol-5-yl]piperidino}-5-(trifluoromethyl)pyridine, 3-chloro-2-[4-[5-(4-chlorophenyl)-2H-pyrazol-3-yl]-1-piperidyl]-5-(trifluoromethyl)pyridine
| Molecular Formula | C20H17Cl2F3N4 |
|---|---|
| Molecular Weight | 440.08 g/mol |
| LogP | 6.1813 |
| Topological Polar Surface Area | 44.81 Ų |
| Hydrogen Bond Donors | 1 |
| Hydrogen Bond Acceptors | 3 |
| Rotatable Bonds | 3 |
| Exact Mass | 440.07825 |
| Heavy Atoms | 29 |
| Complexity | 993.70605 |
Chemical Identifiers
| CAS Number | 321848-27-5 |
|---|---|
| SMILES | C1CN(CCC1C2=CC(=NN2)C3=CC=C(C=C3)Cl)C4=C(C=C(C=N4)C(F)(F)F)Cl |
Product Overview
9L-728 (CAS 321848-27-5), with molecular formula C20H17Cl2F3N4 and molecular weight 440.08 g/mol. IUPAC: 3-chloro-2-[4-[3-(4-chlorophenyl)-1H-pyrazol-5-yl]piperidin-1-yl]-5-(trifluoromethyl)pyridine.
Chemical Property Profile of 9L-728
Property Insights of 9L-728
The XLogP value of 6.1813 indicates that 9L-728 is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. With a topological polar surface area (TPSA) of 44.81 Ų, 9L-728 exhibits relatively low polarity, potentially indicating favorable cell membrane permeability. Following Lipinski's Rule of Five, 9L-728 has 1 hydrogen bond donor(s) and 3 hydrogen bond acceptor(s), which may warrant consideration for formulation optimization.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of 9L-728?
The CAS number of 9L-728 is 321848-27-5.
What is the molecular formula of 9L-728?
The molecular formula of 9L-728 is C20H17Cl2F3N4.
What is the molecular weight of 9L-728?
The molecular weight of 9L-728 is 440.08 g/mol.
Where can I buy 9L-728?
You can request a quote for 9L-728 directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for 9L-728?
Yes, KEHONG BIO provides custom synthesis services for 9L-728 and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.