Crinecerfont (hydrochloride)
TL;DR: Crinecerfont (hydrochloride) (CAS 321839-75-2) is a chemical compound with molecular formula C27H29Cl2FN2OS and molecular weight 518.14 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
4-(2-chloro-4-methoxy-5-methylphenyl)-N-[(1S)-2-cyclopropyl-1-(3-fluoro-4-methylphenyl)ethyl]-5-methyl-N-prop-2-ynyl-1,3-thiazol-2-amine;hydrochloride
Also Known As: Crinecerfont (hydrochloride), Crinecerfont hydrochloride, SSR 125543A, SSR 125543 hydrochloride, HY-106203A
| Molecular Formula | C27H29Cl2FN2OS |
|---|---|
| Molecular Weight | 518.14 g/mol |
| LogP | 7.93926 |
| Topological Polar Surface Area | 25.36 Ų |
| Hydrogen Bond Donors | 0 |
| Hydrogen Bond Acceptors | 4 |
| Rotatable Bonds | 8 |
| Exact Mass | 518.13617 |
| Heavy Atoms | 34 |
| Complexity | 1216.0697 |
Chemical Identifiers
| CAS Number | 321839-75-2 |
|---|---|
| SMILES | CC1=C(C=C(C=C1)[C@H](CC2CC2)N(CC#C)C3=NC(=C(S3)C)C4=C(C=C(C(=C4)C)OC)Cl)F.Cl |
Product Overview
Crinecerfont (hydrochloride) (CAS 321839-75-2), with molecular formula C27H29Cl2FN2OS and molecular weight 518.14 g/mol. IUPAC: 4-(2-chloro-4-methoxy-5-methylphenyl)-N-[(1S)-2-cyclopropyl-1-(3-fluoro-4-methylphenyl)ethyl]-5-methyl-N-prop-2-ynyl-1,3-thiazol-2-amine;hydrochloride.
Chemical Property Profile of Crinecerfont (hydrochloride)
Property Insights of Crinecerfont (hydrochloride)
The XLogP value of 7.93926 indicates that Crinecerfont (hydrochloride) is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. With a topological polar surface area (TPSA) of 25.36 Ų, Crinecerfont (hydrochloride) exhibits relatively low polarity, potentially indicating favorable cell membrane permeability. Following Lipinski's Rule of Five, Crinecerfont (hydrochloride) has 0 hydrogen bond donor(s) and 4 hydrogen bond acceptor(s), which may warrant consideration for formulation optimization.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of Crinecerfont (hydrochloride)?
The CAS number of Crinecerfont (hydrochloride) is 321839-75-2.
What is the molecular formula of Crinecerfont (hydrochloride)?
The molecular formula of Crinecerfont (hydrochloride) is C27H29Cl2FN2OS.
What is the molecular weight of Crinecerfont (hydrochloride)?
The molecular weight of Crinecerfont (hydrochloride) is 518.14 g/mol.
Where can I buy Crinecerfont (hydrochloride)?
You can request a quote for Crinecerfont (hydrochloride) directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for Crinecerfont (hydrochloride)?
Yes, KEHONG BIO provides custom synthesis services for Crinecerfont (hydrochloride) and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.