8H-902
TL;DR: 8H-902 (CAS 321574-35-0) is a chemical compound with molecular formula C20H17ClF4N6O2 and molecular weight 484.10 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
N-[[[3-chloro-5-(trifluoromethyl)-2-pyridinyl]-methylamino]carbamoyl]-N-[(4-fluorophenyl)methyl]-5-methyl-1H-pyrazole-4-carboxamide
Also Known As: 8H-902, 3-{[3-chloro-5-(trifluoromethyl)pyridin-2-yl](methyl)amino}-1-[(4-fluorophenyl)methyl]-1-(3-methyl-1H-pyrazole-4-carbonyl)urea, N-[[[3-chloro-5-(trifluoromethyl)pyridin-2-yl]-methylamino]carbamoyl]-N-[(4-fluorophenyl)methyl]-5-methyl-1H-pyrazole-4-carboxamide, N-({2-[3-chloro-5-(trifluoromethyl)-2-pyridinyl]-2-methylhydrazino}carbonyl)-N-(4-fluorobenzyl)-3-methyl-1H-pyrazole-4-carboxamide
| Molecular Formula | C20H17ClF4N6O2 |
|---|---|
| Molecular Weight | 484.10 g/mol |
| LogP | 4.32782 |
| Topological Polar Surface Area | 94.22 Ų |
| Hydrogen Bond Donors | 2 |
| Hydrogen Bond Acceptors | 5 |
| Rotatable Bonds | 5 |
| Exact Mass | 484.10376 |
| Heavy Atoms | 33 |
| Complexity | 1166.1068 |
Chemical Identifiers
| CAS Number | 321574-35-0 |
|---|---|
| SMILES | CC1=C(C=NN1)C(=O)N(CC2=CC=C(C=C2)F)C(=O)NN(C)C3=C(C=C(C=N3)C(F)(F)F)Cl |
Product Overview
8H-902 (CAS 321574-35-0), with molecular formula C20H17ClF4N6O2 and molecular weight 484.10 g/mol. IUPAC: N-[[[3-chloro-5-(trifluoromethyl)-2-pyridinyl]-methylamino]carbamoyl]-N-[(4-fluorophenyl)methyl]-5-methyl-1H-pyrazole-4-carboxamide.
Chemical Property Profile of 8H-902
Property Insights of 8H-902
The XLogP value of 4.32782 indicates that 8H-902 is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. The TPSA of 94.22 Ų falls within the moderate polarity range, balancing permeability and solubility for 8H-902. Following Lipinski's Rule of Five, 8H-902 has 2 hydrogen bond donor(s) and 5 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of 8H-902?
The CAS number of 8H-902 is 321574-35-0.
What is the molecular formula of 8H-902?
The molecular formula of 8H-902 is C20H17ClF4N6O2.
What is the molecular weight of 8H-902?
The molecular weight of 8H-902 is 484.10 g/mol.
Where can I buy 8H-902?
You can request a quote for 8H-902 directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for 8H-902?
Yes, KEHONG BIO provides custom synthesis services for 8H-902 and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.