![6-(1H-pyrazol-1-yl)-N-[3-(trifluoromethyl)benzyl]nicotinamide structure](/static/products/3215/321533-73-7.webp)
6-(1H-pyrazol-1-yl)-N-[3-(trifluoromethyl)benzyl]nicotinamide
TL;DR: 6-(1H-pyrazol-1-yl)-N-[3-(trifluoromethyl)benzyl]nicotinamide (CAS 321533-73-7) is a chemical compound with molecular formula C17H13F3N4O and molecular weight 346.10 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
6-pyrazol-1-yl-N-[[3-(trifluoromethyl)phenyl]methyl]pyridine-3-carboxamide
Also Known As: 2F-388S, F3406-8153, 6-(1H-pyrazol-1-yl)-N-[3-(trifluoromethyl)benzyl]nicotinamide, 6-(1H-pyrazol-1-yl)-N-{[3-(trifluoromethyl)phenyl]methyl}pyridine-3-carboxamide, 6-(1H-pyrazol-1-yl)-N-(3-(trifluoromethyl)benzyl)nicotinamide
| Molecular Formula | C17H13F3N4O |
|---|---|
| Molecular Weight | 346.10 g/mol |
| LogP | 3.2161 |
| Topological Polar Surface Area | 59.81 Ų |
| Hydrogen Bond Donors | 1 |
| Hydrogen Bond Acceptors | 3 |
| Rotatable Bonds | 4 |
| Exact Mass | 346.10416 |
| Heavy Atoms | 25 |
| Complexity | 858.35443 |
Chemical Identifiers
| CAS Number | 321533-73-7 |
|---|---|
| SMILES | C1=CC(=CC(=C1)C(F)(F)F)CNC(=O)C2=CN=C(C=C2)N3C=CC=N3 |
Product Overview
6-(1H-pyrazol-1-yl)-N-[3-(trifluoromethyl)benzyl]nicotinamide (CAS 321533-73-7), with molecular formula C17H13F3N4O and molecular weight 346.10 g/mol. IUPAC: 6-pyrazol-1-yl-N-[[3-(trifluoromethyl)phenyl]methyl]pyridine-3-carboxamide.
Chemical Property Profile of 6-(1H-pyrazol-1-yl)-N-[3-(trifluoromethyl)benzyl]nicotinamide
Property Insights of 6-(1H-pyrazol-1-yl)-N-[3-(trifluoromethyl)benzyl]nicotinamide
The XLogP value of 3.2161 indicates that 6-(1H-pyrazol-1-yl)-N-[3-(trifluoromethyl)benzyl]nicotinamide is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. With a topological polar surface area (TPSA) of 59.81 Ų, 6-(1H-pyrazol-1-yl)-N-[3-(trifluoromethyl)benzyl]nicotinamide exhibits relatively low polarity, potentially indicating favorable cell membrane permeability. Following Lipinski's Rule of Five, 6-(1H-pyrazol-1-yl)-N-[3-(trifluoromethyl)benzyl]nicotinamide has 1 hydrogen bond donor(s) and 3 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of 6-(1H-pyrazol-1-yl)-N-[3-(trifluoromethyl)benzyl]nicotinamide?
The CAS number of 6-(1H-pyrazol-1-yl)-N-[3-(trifluoromethyl)benzyl]nicotinamide is 321533-73-7.
What is the molecular formula of 6-(1H-pyrazol-1-yl)-N-[3-(trifluoromethyl)benzyl]nicotinamide?
The molecular formula of 6-(1H-pyrazol-1-yl)-N-[3-(trifluoromethyl)benzyl]nicotinamide is C17H13F3N4O.
What is the molecular weight of 6-(1H-pyrazol-1-yl)-N-[3-(trifluoromethyl)benzyl]nicotinamide?
The molecular weight of 6-(1H-pyrazol-1-yl)-N-[3-(trifluoromethyl)benzyl]nicotinamide is 346.10 g/mol.
Where can I buy 6-(1H-pyrazol-1-yl)-N-[3-(trifluoromethyl)benzyl]nicotinamide?
You can request a quote for 6-(1H-pyrazol-1-yl)-N-[3-(trifluoromethyl)benzyl]nicotinamide directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for 6-(1H-pyrazol-1-yl)-N-[3-(trifluoromethyl)benzyl]nicotinamide?
Yes, KEHONG BIO provides custom synthesis services for 6-(1H-pyrazol-1-yl)-N-[3-(trifluoromethyl)benzyl]nicotinamide and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.