1J-901 structure

1J-901

TL;DR: 1J-901 (CAS 321433-29-8) is a chemical compound with molecular formula C16H12ClF3N6O2S and molecular weight 444.04 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.

3-[2-[[3-chloro-5-(trifluoromethyl)-2-pyridinyl]amino]ethyl]-6-pyrimidin-2-ylsulfanyl-1H-pyrimidine-2,4-dione

Also Known As: 1J-901, 3-[2-[[3-chloro-5-(trifluoromethyl)pyridin-2-yl]amino]ethyl]-6-pyrimidin-2-ylsulfanyl-1H-pyrimidine-2,4-dione, 3-(2-{[3-chloro-5-(trifluoromethyl)pyridin-2-yl]amino}ethyl)-6-(pyrimidin-2-ylsulfanyl)-1,2,3,4-tetrahydropyrimidine-2,4-dione, 3-(2-{[3-chloro-5-(trifluoromethyl)-2-pyridinyl]amino}ethyl)-6-(2-pyrimidinylsulfanyl)-2,4(1H,3H)-pyrimidinedione

CAS: 321433-29-8
Molecular Formula C16H12ClF3N6O2S
Molecular Weight 444.04 g/mol
LogP 2.6571
Topological Polar Surface Area 105.56 Ų
Hydrogen Bond Donors 2
Hydrogen Bond Acceptors 7
Rotatable Bonds 6
Exact Mass 444.0383
Heavy Atoms 29
Complexity 1088.8684

Chemical Identifiers

CAS Number 321433-29-8
SMILES C1=CN=C(N=C1)SC2=CC(=O)N(C(=O)N2)CCNC3=C(C=C(C=N3)C(F)(F)F)Cl

Product Overview

1J-901 (CAS 321433-29-8), with molecular formula C16H12ClF3N6O2S and molecular weight 444.04 g/mol. IUPAC: 3-[2-[[3-chloro-5-(trifluoromethyl)-2-pyridinyl]amino]ethyl]-6-pyrimidin-2-ylsulfanyl-1H-pyrimidine-2,4-dione.

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Safety Data Sheet (MSDS / SDS) View the Laboratory Chemical Safety Summary (LCSS) on PubChem — includes GHS classifications, hazard statements, first aid measures, and handling precautions.
View MSDS →

Chemical Property Profile of 1J-901

XLogP
2.6571
TPSA (Topological Polar Surface Area)
105.56
Hydrogen Bond Donors
2
Hydrogen Bond Acceptors
7
Rotatable Bonds
6
Heavy Atoms
29
Complexity
1088.8684
Exact Mass
444.0383
Monoisotopic Mass
444.0383
Data Source: Chemical property values are referenced from PubChem, the world's largest open chemistry database maintained by the National Center for Biotechnology Information (NCBI), U.S. National Library of Medicine.

Property Insights of 1J-901

The XLogP value of 2.6571 suggests moderate lipophilicity, balancing water solubility and membrane permeability for 1J-901. The TPSA of 105.56 Ų falls within the moderate polarity range, balancing permeability and solubility for 1J-901. Following Lipinski's Rule of Five, 1J-901 has 2 hydrogen bond donor(s) and 7 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.

Frequently Asked Questions

What is the typical lead time for this product?
Lead time typically ranges from 3-7 business days for in-stock items. For larger quantities or custom orders, please contact us for specific lead times.
Can you provide samples for testing?
Yes, we offer sample quantities for quality testing. Please submit an inquiry with your requirements and we will arrange samples accordingly.
What documentation do you provide with the product?
We provide COA (Certificate of Analysis), MSDS (Material Safety Data Sheet), and technical data sheets with each shipment.
Do you ship internationally?
Yes, we ship to most countries worldwide. Shipping costs and delivery times vary by location. Please contact us for specific shipping information.

Frequently Asked Questions

What is the CAS number of 1J-901?

The CAS number of 1J-901 is 321433-29-8.

What is the molecular formula of 1J-901?

The molecular formula of 1J-901 is C16H12ClF3N6O2S.

What is the molecular weight of 1J-901?

The molecular weight of 1J-901 is 444.04 g/mol.

Where can I buy 1J-901?

You can request a quote for 1J-901 directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.

Does KEHONG BIO offer custom synthesis for 1J-901?

Yes, KEHONG BIO provides custom synthesis services for 1J-901 and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.

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