1H-940
TL;DR: 1H-940 (CAS 321432-22-8) is a chemical compound with molecular formula C16H20ClF3N4 and molecular weight 360.13 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
1-[1-[3-chloro-5-(trifluoromethyl)-2-pyridinyl]-3,6-dihydro-2H-pyridin-4-yl]-4-methylpiperazine
Also Known As: 1H-940, 1-{1-[3-chloro-5-(trifluoromethyl)-2-pyridinyl]-1,2,3,6-tetrahydro-4-pyridinyl}-4-methylpiperazine, 1-[1-[3-chloro-5-(trifluoromethyl)pyridin-2-yl]-3,6-dihydro-2H-pyridin-4-yl]-4-methylpiperazine, 3'-chloro-4-(4-methylpiperazin-1-yl)-5'-(trifluoromethyl)-3,6-dihydro-2H-1,2'-bipyridine, 1-[1-[3-chloro-5-(trifluoromethyl)pyridin-2-yl]-3,6-dihydro-2H-pyridin-4-yl]-4-methyl-piperazine
| Molecular Formula | C16H20ClF3N4 |
|---|---|
| Molecular Weight | 360.13 g/mol |
| LogP | 3.0952 |
| Topological Polar Surface Area | 22.61 Ų |
| Hydrogen Bond Donors | 0 |
| Hydrogen Bond Acceptors | 4 |
| Rotatable Bonds | 2 |
| Exact Mass | 360.13287 |
| Heavy Atoms | 24 |
| Complexity | 624.23883 |
Chemical Identifiers
| CAS Number | 321432-22-8 |
|---|---|
| SMILES | CN1CCN(CC1)C2=CCN(CC2)C3=C(C=C(C=N3)C(F)(F)F)Cl |
Product Overview
1H-940 (CAS 321432-22-8), with molecular formula C16H20ClF3N4 and molecular weight 360.13 g/mol. IUPAC: 1-[1-[3-chloro-5-(trifluoromethyl)-2-pyridinyl]-3,6-dihydro-2H-pyridin-4-yl]-4-methylpiperazine.
Chemical Property Profile of 1H-940
Property Insights of 1H-940
The XLogP value of 3.0952 indicates that 1H-940 is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. With a topological polar surface area (TPSA) of 22.61 Ų, 1H-940 exhibits relatively low polarity, potentially indicating favorable cell membrane permeability. Following Lipinski's Rule of Five, 1H-940 has 0 hydrogen bond donor(s) and 4 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of 1H-940?
The CAS number of 1H-940 is 321432-22-8.
What is the molecular formula of 1H-940?
The molecular formula of 1H-940 is C16H20ClF3N4.
What is the molecular weight of 1H-940?
The molecular weight of 1H-940 is 360.13 g/mol.
Where can I buy 1H-940?
You can request a quote for 1H-940 directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for 1H-940?
Yes, KEHONG BIO provides custom synthesis services for 1H-940 and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.