1G-404S
TL;DR: 1G-404S (CAS 321430-03-9) is a chemical compound with molecular formula C23H13Cl2F3N2O2S and molecular weight 508.00 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
4-[4-(2,4-dichlorophenyl)-1,3-thiazol-2-yl]-N-[4-(trifluoromethoxy)phenyl]benzamide
Also Known As: 1G-404S, 4-[4-(2,4-dichlorophenyl)-1,3-thiazol-2-yl]-N-[4-(trifluoromethoxy)phenyl]benzamide, 4-[4-(2,4-dichlorophenyl)-1,3-thiazol-2-yl]-N-[4-(trifluoromethoxy)phenyl]benzenecarboxamide
| Molecular Formula | C23H13Cl2F3N2O2S |
|---|---|
| Molecular Weight | 508.00 g/mol |
| LogP | 7.9348 |
| Topological Polar Surface Area | 51.22 Ų |
| Hydrogen Bond Donors | 1 |
| Hydrogen Bond Acceptors | 4 |
| Rotatable Bonds | 5 |
| Exact Mass | 508.0027 |
| Heavy Atoms | 33 |
| Complexity | 1290.5619 |
Chemical Identifiers
| CAS Number | 321430-03-9 |
|---|---|
| SMILES | C1=CC(=CC=C1C2=NC(=CS2)C3=C(C=C(C=C3)Cl)Cl)C(=O)NC4=CC=C(C=C4)OC(F)(F)F |
Product Overview
1G-404S (CAS 321430-03-9), with molecular formula C23H13Cl2F3N2O2S and molecular weight 508.00 g/mol. IUPAC: 4-[4-(2,4-dichlorophenyl)-1,3-thiazol-2-yl]-N-[4-(trifluoromethoxy)phenyl]benzamide.
Chemical Property Profile of 1G-404S
Property Insights of 1G-404S
The XLogP value of 7.9348 indicates that 1G-404S is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. With a topological polar surface area (TPSA) of 51.22 Ų, 1G-404S exhibits relatively low polarity, potentially indicating favorable cell membrane permeability. Following Lipinski's Rule of Five, 1G-404S has 1 hydrogen bond donor(s) and 4 hydrogen bond acceptor(s), which may warrant consideration for formulation optimization.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of 1G-404S?
The CAS number of 1G-404S is 321430-03-9.
What is the molecular formula of 1G-404S?
The molecular formula of 1G-404S is C23H13Cl2F3N2O2S.
What is the molecular weight of 1G-404S?
The molecular weight of 1G-404S is 508.00 g/mol.
Where can I buy 1G-404S?
You can request a quote for 1G-404S directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for 1G-404S?
Yes, KEHONG BIO provides custom synthesis services for 1G-404S and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.