5-fluoro-3-hydroxyimino-1H-indol-2-one
TL;DR: 5-fluoro-3-hydroxyimino-1H-indol-2-one (CAS 319-64-2) is a chemical compound with molecular formula C8H5FN2O2 and molecular weight 180.03 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
5-fluoro-3-nitroso-1H-indol-2-ol
Also Known As: Sunitinib Impurity 68, 5-Fluoroisatin-3-oxime, 5-fluoro-3-(hydroxyamino)indol-2-one, 5-fluoro-1H-indole-2,3-dione 3-oxime, 5-fluoro-3-nitroso-1H-indol-2-ol
| Molecular Formula | C8H5FN2O2 |
|---|---|
| Molecular Weight | 180.03 g/mol |
| LogP | 2.4105 |
| Topological Polar Surface Area | 65.45 Ų |
| Hydrogen Bond Donors | 2 |
| Hydrogen Bond Acceptors | 3 |
| Rotatable Bonds | 1 |
| Exact Mass | 180.03351 |
| Heavy Atoms | 13 |
| Complexity | 478.1939 |
Chemical Identifiers
| CAS Number | 319-64-2 |
|---|---|
| SMILES | C1=CC2=C(C=C1F)C(=C(N2)O)N=O |
Product Overview
5-fluoro-3-hydroxyimino-1H-indol-2-one (CAS 319-64-2), with molecular formula C8H5FN2O2 and molecular weight 180.03 g/mol. IUPAC: 5-fluoro-3-nitroso-1H-indol-2-ol.
Chemical Property Profile of 5-fluoro-3-hydroxyimino-1H-indol-2-one
Property Insights of 5-fluoro-3-hydroxyimino-1H-indol-2-one
The XLogP value of 2.4105 suggests moderate lipophilicity, balancing water solubility and membrane permeability for 5-fluoro-3-hydroxyimino-1H-indol-2-one. The TPSA of 65.45 Ų falls within the moderate polarity range, balancing permeability and solubility for 5-fluoro-3-hydroxyimino-1H-indol-2-one. Following Lipinski's Rule of Five, 5-fluoro-3-hydroxyimino-1H-indol-2-one has 2 hydrogen bond donor(s) and 3 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of 5-fluoro-3-hydroxyimino-1H-indol-2-one?
The CAS number of 5-fluoro-3-hydroxyimino-1H-indol-2-one is 319-64-2.
What is the molecular formula of 5-fluoro-3-hydroxyimino-1H-indol-2-one?
The molecular formula of 5-fluoro-3-hydroxyimino-1H-indol-2-one is C8H5FN2O2.
What is the molecular weight of 5-fluoro-3-hydroxyimino-1H-indol-2-one?
The molecular weight of 5-fluoro-3-hydroxyimino-1H-indol-2-one is 180.03 g/mol.
Where can I buy 5-fluoro-3-hydroxyimino-1H-indol-2-one?
You can request a quote for 5-fluoro-3-hydroxyimino-1H-indol-2-one directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for 5-fluoro-3-hydroxyimino-1H-indol-2-one?
Yes, KEHONG BIO provides custom synthesis services for 5-fluoro-3-hydroxyimino-1H-indol-2-one and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.