7H-944
TL;DR: 7H-944 (CAS 318951-75-6) is a chemical compound with molecular formula C19H14ClF4N5O and molecular weight 439.08 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
3-chloro-N-[[3-[1-(4-fluorophenyl)pyrazol-3-yl]-4,5-dihydro-1,2-oxazol-5-yl]methyl]-5-(trifluoromethyl)pyridin-2-amine
Also Known As: 7H-944, 3-chloro-N-({3-[1-(4-fluorophenyl)-1H-pyrazol-3-yl]-4,5-dihydro-5-isoxazolyl}methyl)-5-(trifluoromethyl)-2-pyridinamine, 3-chloro-N-({3-[1-(4-fluorophenyl)-1H-pyrazol-3-yl]-4,5-dihydro-1,2-oxazol-5-yl}methyl)-5-(trifluoromethyl)pyridin-2-amine, 3-chloro-N-[[3-[1-(4-fluorophenyl)pyrazol-3-yl]-4,5-dihydro-1,2-oxazol-5-yl]methyl]-5-(trifluoromethyl)pyridin-2-amine, 3-chloro-N-({3-[1-(4-fluorophenyl)pyrazol-3-yl]-4,5-dihydro-1,2-oxazol-5-yl}methyl)-5-(trifluoromethyl)pyridin-2-amine
| Molecular Formula | C19H14ClF4N5O |
|---|---|
| Molecular Weight | 439.08 g/mol |
| LogP | 4.6837 |
| Topological Polar Surface Area | 64.33 Ų |
| Hydrogen Bond Donors | 1 |
| Hydrogen Bond Acceptors | 5 |
| Rotatable Bonds | 5 |
| Exact Mass | 439.0823 |
| Heavy Atoms | 30 |
| Complexity | 1081.2739 |
Chemical Identifiers
| CAS Number | 318951-75-6 |
|---|---|
| SMILES | C1C(ON=C1C2=NN(C=C2)C3=CC=C(C=C3)F)CNC4=C(C=C(C=N4)C(F)(F)F)Cl |
Product Overview
7H-944 (CAS 318951-75-6), with molecular formula C19H14ClF4N5O and molecular weight 439.08 g/mol. IUPAC: 3-chloro-N-[[3-[1-(4-fluorophenyl)pyrazol-3-yl]-4,5-dihydro-1,2-oxazol-5-yl]methyl]-5-(trifluoromethyl)pyridin-2-amine.
Chemical Property Profile of 7H-944
Property Insights of 7H-944
The XLogP value of 4.6837 indicates that 7H-944 is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. The TPSA of 64.33 Ų falls within the moderate polarity range, balancing permeability and solubility for 7H-944. Following Lipinski's Rule of Five, 7H-944 has 1 hydrogen bond donor(s) and 5 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of 7H-944?
The CAS number of 7H-944 is 318951-75-6.
What is the molecular formula of 7H-944?
The molecular formula of 7H-944 is C19H14ClF4N5O.
What is the molecular weight of 7H-944?
The molecular weight of 7H-944 is 439.08 g/mol.
Where can I buy 7H-944?
You can request a quote for 7H-944 directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for 7H-944?
Yes, KEHONG BIO provides custom synthesis services for 7H-944 and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.