THP hydrochloride structure

THP hydrochloride

TL;DR: THP hydrochloride (CAS 3184-36-9) is a chemical compound with molecular formula C16H18ClNO4 and molecular weight 323.09 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.

1-[(3,4-dihydroxyphenyl)methyl]-1,2,3,4-tetrahydroisoquinolin-2-ium-6,7-diol chloride

Also Known As: THP hydrochloride, Tetrahydropapaveroline, hydrochloride, Tetrahydropapaveroline hydrochloride, 1-((3,4-Dihydroxyphenyl)methyl)-1,2,3,4-tetrahydroisoquinoline-6,7-diol hydrochloride, 1-Benzyl-3',4',6,7-tetrahydroxy-1,2,3,4-tetrahydroisoquinoline, hydrochloride

CAS: 3184-36-9
Molecular Formula C16H18ClNO4
Molecular Weight 323.09 g/mol
LogP -2.08
Topological Polar Surface Area 97.5 Ų
Hydrogen Bond Donors 5
Hydrogen Bond Acceptors 5
Rotatable Bonds 2
Exact Mass 323.09244
Heavy Atoms 22
Complexity 353.0

Chemical Identifiers

CAS Number 3184-36-9
SMILES C1C[NH2+]C(C2=CC(=C(C=C21)O)O)CC3=CC(=C(C=C3)O)O.[Cl-]
InChIKey WSIHAFYVFLJCQH-UHFFFAOYSA-N

Product Overview

THP hydrochloride (CAS 3184-36-9), with molecular formula C16H18ClNO4 and molecular weight 323.09 g/mol. IUPAC: 1-[(3,4-dihydroxyphenyl)methyl]-1,2,3,4-tetrahydroisoquinolin-2-ium-6,7-diol chloride.

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Safety Data Sheet (MSDS / SDS) View the Laboratory Chemical Safety Summary (LCSS) on PubChem — includes GHS classifications, hazard statements, first aid measures, and handling precautions.
View MSDS →

Chemical Property Profile of THP hydrochloride

XLogP
-2.08
TPSA (Topological Polar Surface Area)
97.5
Hydrogen Bond Donors
5
Hydrogen Bond Acceptors
5
Rotatable Bonds
2
Heavy Atoms
22
Complexity
353.0
Exact Mass
323.09244
Monoisotopic Mass
323.09244
Data Source: Chemical property values are referenced from PubChem, the world's largest open chemistry database maintained by the National Center for Biotechnology Information (NCBI), U.S. National Library of Medicine.

Property Insights of THP hydrochloride

The XLogP value of -2.08 indicates that THP hydrochloride is hydrophilic (water-soluble), making it suitable for aqueous formulations and biological assay applications. The TPSA of 97.5 Ų falls within the moderate polarity range, balancing permeability and solubility for THP hydrochloride. Following Lipinski's Rule of Five, THP hydrochloride has 5 hydrogen bond donor(s) and 5 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.

Frequently Asked Questions

What is the typical lead time for this product?
Lead time typically ranges from 3-7 business days for in-stock items. For larger quantities or custom orders, please contact us for specific lead times.
Can you provide samples for testing?
Yes, we offer sample quantities for quality testing. Please submit an inquiry with your requirements and we will arrange samples accordingly.
What documentation do you provide with the product?
We provide COA (Certificate of Analysis), MSDS (Material Safety Data Sheet), and technical data sheets with each shipment.
Do you ship internationally?
Yes, we ship to most countries worldwide. Shipping costs and delivery times vary by location. Please contact us for specific shipping information.

Frequently Asked Questions

What is the CAS number of THP hydrochloride?

The CAS number of THP hydrochloride is 3184-36-9.

What is the molecular formula of THP hydrochloride?

The molecular formula of THP hydrochloride is C16H18ClNO4.

What is the molecular weight of THP hydrochloride?

The molecular weight of THP hydrochloride is 323.09 g/mol.

Where can I buy THP hydrochloride?

You can request a quote for THP hydrochloride directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.

Does KEHONG BIO offer custom synthesis for THP hydrochloride?

Yes, KEHONG BIO provides custom synthesis services for THP hydrochloride and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.

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