2-(4-chlorophenyl)-5-(1H-pyrazol-3-yl)-1,3-thiazole
TL;DR: 2-(4-chlorophenyl)-5-(1H-pyrazol-3-yl)-1,3-thiazole (CAS 318248-75-8) is a chemical compound with molecular formula C12H8ClN3S and molecular weight 261.01 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
2-(4-chlorophenyl)-5-(1H-pyrazol-5-yl)-1,3-thiazole
Also Known As: 2-(4-chlorophenyl)-5-(1H-pyrazol-3-yl)-1,3-thiazole, 2-(4-chlorophenyl)-5-(1H-pyrazol-5-yl)-1,3-thiazole, 4M-013
| Molecular Formula | C12H8ClN3S |
|---|---|
| Molecular Weight | 261.01 g/mol |
| LogP | 3.8536 |
| Topological Polar Surface Area | 41.57 Ų |
| Hydrogen Bond Donors | 1 |
| Hydrogen Bond Acceptors | 3 |
| Rotatable Bonds | 2 |
| Exact Mass | 261.01276 |
| Heavy Atoms | 17 |
| Complexity | 613.5104 |
Chemical Identifiers
| CAS Number | 318248-75-8 |
|---|---|
| SMILES | C1=CC(=CC=C1C2=NC=C(S2)C3=CC=NN3)Cl |
Product Overview
2-(4-chlorophenyl)-5-(1H-pyrazol-3-yl)-1,3-thiazole (CAS 318248-75-8), with molecular formula C12H8ClN3S and molecular weight 261.01 g/mol. IUPAC: 2-(4-chlorophenyl)-5-(1H-pyrazol-5-yl)-1,3-thiazole.
Chemical Property Profile of 2-(4-chlorophenyl)-5-(1H-pyrazol-3-yl)-1,3-thiazole
Property Insights of 2-(4-chlorophenyl)-5-(1H-pyrazol-3-yl)-1,3-thiazole
The XLogP value of 3.8536 indicates that 2-(4-chlorophenyl)-5-(1H-pyrazol-3-yl)-1,3-thiazole is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. With a topological polar surface area (TPSA) of 41.57 Ų, 2-(4-chlorophenyl)-5-(1H-pyrazol-3-yl)-1,3-thiazole exhibits relatively low polarity, potentially indicating favorable cell membrane permeability. Following Lipinski's Rule of Five, 2-(4-chlorophenyl)-5-(1H-pyrazol-3-yl)-1,3-thiazole has 1 hydrogen bond donor(s) and 3 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of 2-(4-chlorophenyl)-5-(1H-pyrazol-3-yl)-1,3-thiazole?
The CAS number of 2-(4-chlorophenyl)-5-(1H-pyrazol-3-yl)-1,3-thiazole is 318248-75-8.
What is the molecular formula of 2-(4-chlorophenyl)-5-(1H-pyrazol-3-yl)-1,3-thiazole?
The molecular formula of 2-(4-chlorophenyl)-5-(1H-pyrazol-3-yl)-1,3-thiazole is C12H8ClN3S.
What is the molecular weight of 2-(4-chlorophenyl)-5-(1H-pyrazol-3-yl)-1,3-thiazole?
The molecular weight of 2-(4-chlorophenyl)-5-(1H-pyrazol-3-yl)-1,3-thiazole is 261.01 g/mol.
Where can I buy 2-(4-chlorophenyl)-5-(1H-pyrazol-3-yl)-1,3-thiazole?
You can request a quote for 2-(4-chlorophenyl)-5-(1H-pyrazol-3-yl)-1,3-thiazole directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for 2-(4-chlorophenyl)-5-(1H-pyrazol-3-yl)-1,3-thiazole?
Yes, KEHONG BIO provides custom synthesis services for 2-(4-chlorophenyl)-5-(1H-pyrazol-3-yl)-1,3-thiazole and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.