![3-Amino-2-[4-[3-chloro-5-(trifluoromethyl)pyridin-2-yl]piperazin-1-yl]pyridine hydrochloride structure](/static/products/3178/317822-49-4.webp)
3-Amino-2-[4-[3-chloro-5-(trifluoromethyl)pyridin-2-yl]piperazin-1-yl]pyridine hydrochloride
TL;DR: 3-Amino-2-[4-[3-chloro-5-(trifluoromethyl)pyridin-2-yl]piperazin-1-yl]pyridine hydrochloride (CAS 317822-49-4) is a chemical compound with molecular formula C15H16Cl2F3N5 and molecular weight 393.07 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
2-[4-[3-chloro-5-(trifluoromethyl)-2-pyridinyl]piperazin-1-yl]pyridin-3-amine;hydrochloride
Also Known As: 3-Amino-2-[4-[3-chloro-5-(trifluoromethyl)pyridin-2-yl]piperazin-1-yl]pyridine hydrochloride, 2-(4-(3-chloro-5-(trifluoromethyl)pyridin-2-yl)piperazin-1-yl)pyridin-3-amine hydrochloride, 2-[4-[3-chloro-5-(trifluoromethyl)pyridin-2-yl]piperazin-1-yl]pyridin-3-amine Hydrochloride, 2-{4-[3-chloro-5-(trifluoromethyl)pyridin-2-yl]piperazin-1-yl}pyridin-3-amine hydrochloride, 2-[4-[3-chloro-5-(trifluoromethyl)-2-pyridyl]piperazin-1-yl]pyridin-3-amine;hydrochloride
| Molecular Formula | C15H16Cl2F3N5 |
|---|---|
| Molecular Weight | 393.07 g/mol |
| LogP | 3.4794 |
| Topological Polar Surface Area | 58.28 Ų |
| Hydrogen Bond Donors | 1 |
| Hydrogen Bond Acceptors | 5 |
| Rotatable Bonds | 2 |
| Exact Mass | 393.0735 |
| Heavy Atoms | 25 |
| Complexity | 733.34705 |
Chemical Identifiers
| CAS Number | 317822-49-4 |
|---|---|
| SMILES | C1CN(CCN1C2=C(C=CC=N2)N)C3=C(C=C(C=N3)C(F)(F)F)Cl.Cl |
Product Overview
3-Amino-2-[4-[3-chloro-5-(trifluoromethyl)pyridin-2-yl]piperazin-1-yl]pyridine hydrochloride (CAS 317822-49-4), with molecular formula C15H16Cl2F3N5 and molecular weight 393.07 g/mol. IUPAC: 2-[4-[3-chloro-5-(trifluoromethyl)-2-pyridinyl]piperazin-1-yl]pyridin-3-amine;hydrochloride.
Chemical Property Profile of 3-Amino-2-[4-[3-chloro-5-(trifluoromethyl)pyridin-2-yl]piperazin-1-yl]pyridine hydrochloride
Property Insights of 3-Amino-2-[4-[3-chloro-5-(trifluoromethyl)pyridin-2-yl]piperazin-1-yl]pyridine hydrochloride
The XLogP value of 3.4794 indicates that 3-Amino-2-[4-[3-chloro-5-(trifluoromethyl)pyridin-2-yl]piperazin-1-yl]pyridine hydrochloride is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. With a topological polar surface area (TPSA) of 58.28 Ų, 3-Amino-2-[4-[3-chloro-5-(trifluoromethyl)pyridin-2-yl]piperazin-1-yl]pyridine hydrochloride exhibits relatively low polarity, potentially indicating favorable cell membrane permeability. Following Lipinski's Rule of Five, 3-Amino-2-[4-[3-chloro-5-(trifluoromethyl)pyridin-2-yl]piperazin-1-yl]pyridine hydrochloride has 1 hydrogen bond donor(s) and 5 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of 3-Amino-2-[4-[3-chloro-5-(trifluoromethyl)pyridin-2-yl]piperazin-1-yl]pyridine hydrochloride?
The CAS number of 3-Amino-2-[4-[3-chloro-5-(trifluoromethyl)pyridin-2-yl]piperazin-1-yl]pyridine hydrochloride is 317822-49-4.
What is the molecular formula of 3-Amino-2-[4-[3-chloro-5-(trifluoromethyl)pyridin-2-yl]piperazin-1-yl]pyridine hydrochloride?
The molecular formula of 3-Amino-2-[4-[3-chloro-5-(trifluoromethyl)pyridin-2-yl]piperazin-1-yl]pyridine hydrochloride is C15H16Cl2F3N5.
What is the molecular weight of 3-Amino-2-[4-[3-chloro-5-(trifluoromethyl)pyridin-2-yl]piperazin-1-yl]pyridine hydrochloride?
The molecular weight of 3-Amino-2-[4-[3-chloro-5-(trifluoromethyl)pyridin-2-yl]piperazin-1-yl]pyridine hydrochloride is 393.07 g/mol.
Where can I buy 3-Amino-2-[4-[3-chloro-5-(trifluoromethyl)pyridin-2-yl]piperazin-1-yl]pyridine hydrochloride?
You can request a quote for 3-Amino-2-[4-[3-chloro-5-(trifluoromethyl)pyridin-2-yl]piperazin-1-yl]pyridine hydrochloride directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for 3-Amino-2-[4-[3-chloro-5-(trifluoromethyl)pyridin-2-yl]piperazin-1-yl]pyridine hydrochloride?
Yes, KEHONG BIO provides custom synthesis services for 3-Amino-2-[4-[3-chloro-5-(trifluoromethyl)pyridin-2-yl]piperazin-1-yl]pyridine hydrochloride and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.