12G-387S
TL;DR: 12G-387S (CAS 317377-86-9) is a chemical compound with molecular formula C18H16F4N2O3S and molecular weight 416.08 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
1-(4-fluorophenyl)sulfonyl-N-[3-(trifluoromethyl)phenyl]pyrrolidine-2-carboxamide
Also Known As: 12G-387S, 1-(4-fluorophenyl)sulfonyl-N-[3-(trifluoromethyl)phenyl]pyrrolidine-2-carboxamide, 1-(4-fluorobenzenesulfonyl)-N-[3-(trifluoromethyl)phenyl]pyrrolidine-2-carboxamide, 1-((4-Fluorophenyl)sulfonyl)-N-(3-(trifluoromethyl)phenyl)pyrrolidine-2-carboxamide, 1-[(4-fluorophenyl)sulfonyl]-N-[3-(trifluoromethyl)phenyl]-2-pyrrolidinecarboxamide
| Molecular Formula | C18H16F4N2O3S |
|---|---|
| Molecular Weight | 416.08 g/mol |
| LogP | 3.6363 |
| Topological Polar Surface Area | 66.48 Ų |
| Hydrogen Bond Donors | 1 |
| Hydrogen Bond Acceptors | 3 |
| Rotatable Bonds | 4 |
| Exact Mass | 416.0818 |
| Heavy Atoms | 28 |
| Complexity | 975.0704 |
Chemical Identifiers
| CAS Number | 317377-86-9 |
|---|---|
| SMILES | C1CC(N(C1)S(=O)(=O)C2=CC=C(C=C2)F)C(=O)NC3=CC=CC(=C3)C(F)(F)F |
Product Overview
12G-387S (CAS 317377-86-9), with molecular formula C18H16F4N2O3S and molecular weight 416.08 g/mol. IUPAC: 1-(4-fluorophenyl)sulfonyl-N-[3-(trifluoromethyl)phenyl]pyrrolidine-2-carboxamide.
Chemical Property Profile of 12G-387S
Property Insights of 12G-387S
The XLogP value of 3.6363 indicates that 12G-387S is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. The TPSA of 66.48 Ų falls within the moderate polarity range, balancing permeability and solubility for 12G-387S. Following Lipinski's Rule of Five, 12G-387S has 1 hydrogen bond donor(s) and 3 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of 12G-387S?
The CAS number of 12G-387S is 317377-86-9.
What is the molecular formula of 12G-387S?
The molecular formula of 12G-387S is C18H16F4N2O3S.
What is the molecular weight of 12G-387S?
The molecular weight of 12G-387S is 416.08 g/mol.
Where can I buy 12G-387S?
You can request a quote for 12G-387S directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for 12G-387S?
Yes, KEHONG BIO provides custom synthesis services for 12G-387S and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.