12G-386S
TL;DR: 12G-386S (CAS 317377-84-7) is a chemical compound with molecular formula C18H16F4N2O4S and molecular weight 432.08 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
1-(4-fluorophenyl)sulfonyl-N-[4-(trifluoromethoxy)phenyl]pyrrolidine-2-carboxamide
Also Known As: 12G-386S, 1-(4-fluorobenzenesulfonyl)-N-[4-(trifluoromethoxy)phenyl]pyrrolidine-2-carboxamide, 1-(4-fluorophenyl)sulfonyl-N-[4-(trifluoromethoxy)phenyl]pyrrolidine-2-carboxamide, 1-[(4-fluorophenyl)sulfonyl]-N-[4-(trifluoromethoxy)phenyl]-2-pyrrolidinecarboxamide, 1-((4-Fluorophenyl)sulfonyl)-N-(4-(trifluoromethoxy)phenyl)pyrrolidine-2-carboxamide
| Molecular Formula | C18H16F4N2O4S |
|---|---|
| Molecular Weight | 432.08 g/mol |
| LogP | 3.5161 |
| Topological Polar Surface Area | 75.71 Ų |
| Hydrogen Bond Donors | 1 |
| Hydrogen Bond Acceptors | 4 |
| Rotatable Bonds | 5 |
| Exact Mass | 432.0767 |
| Heavy Atoms | 29 |
| Complexity | 976.41583 |
Chemical Identifiers
| CAS Number | 317377-84-7 |
|---|---|
| SMILES | C1CC(N(C1)S(=O)(=O)C2=CC=C(C=C2)F)C(=O)NC3=CC=C(C=C3)OC(F)(F)F |
Product Overview
12G-386S (CAS 317377-84-7), with molecular formula C18H16F4N2O4S and molecular weight 432.08 g/mol. IUPAC: 1-(4-fluorophenyl)sulfonyl-N-[4-(trifluoromethoxy)phenyl]pyrrolidine-2-carboxamide.
Chemical Property Profile of 12G-386S
Property Insights of 12G-386S
The XLogP value of 3.5161 indicates that 12G-386S is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. The TPSA of 75.71 Ų falls within the moderate polarity range, balancing permeability and solubility for 12G-386S. Following Lipinski's Rule of Five, 12G-386S has 1 hydrogen bond donor(s) and 4 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of 12G-386S?
The CAS number of 12G-386S is 317377-84-7.
What is the molecular formula of 12G-386S?
The molecular formula of 12G-386S is C18H16F4N2O4S.
What is the molecular weight of 12G-386S?
The molecular weight of 12G-386S is 432.08 g/mol.
Where can I buy 12G-386S?
You can request a quote for 12G-386S directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for 12G-386S?
Yes, KEHONG BIO provides custom synthesis services for 12G-386S and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.