JK184
TL;DR: JK184 (CAS 315703-52-7) is a chemical compound with molecular formula C19H18N4OS and molecular weight 350.12 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
N-(4-ethoxyphenyl)-4-(2-methylimidazo[1,2-a]pyridin-3-yl)-1,3-thiazol-2-amine
Also Known As: N-(4-ethoxyphenyl)-4-(2-methylimidazo[1,2-a]pyridin-3-yl)thiazol-2-amine, HH SIGNALING ANTAGONIST VII, Hh Signaling Antagonist VII, JK184, s6565, JK184/ JK-184
| Molecular Formula | C19H18N4OS |
|---|---|
| Molecular Weight | 350.12 g/mol |
| LogP | 4.90852 |
| Topological Polar Surface Area | 51.45 Ų |
| Hydrogen Bond Donors | 1 |
| Hydrogen Bond Acceptors | 5 |
| Rotatable Bonds | 5 |
| Exact Mass | 350.12012 |
| Heavy Atoms | 25 |
| Complexity | 1003.8763 |
Chemical Identifiers
| CAS Number | 315703-52-7 |
|---|---|
| SMILES | CCOC1=CC=C(C=C1)NC2=NC(=CS2)C3=C(N=C4N3C=CC=C4)C |
Product Overview
JK184 (CAS 315703-52-7), with molecular formula C19H18N4OS and molecular weight 350.12 g/mol. IUPAC: N-(4-ethoxyphenyl)-4-(2-methylimidazo[1,2-a]pyridin-3-yl)-1,3-thiazol-2-amine.
Chemical Property Profile of JK184
Property Insights of JK184
The XLogP value of 4.90852 indicates that JK184 is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. With a topological polar surface area (TPSA) of 51.45 Ų, JK184 exhibits relatively low polarity, potentially indicating favorable cell membrane permeability. Following Lipinski's Rule of Five, JK184 has 1 hydrogen bond donor(s) and 5 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of JK184?
The CAS number of JK184 is 315703-52-7.
What is the molecular formula of JK184?
The molecular formula of JK184 is C19H18N4OS.
What is the molecular weight of JK184?
The molecular weight of JK184 is 350.12 g/mol.
Where can I buy JK184?
You can request a quote for JK184 directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for JK184?
Yes, KEHONG BIO provides custom synthesis services for JK184 and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.