F1143-5780
TL;DR: F1143-5780 (CAS 315693-83-5) is a chemical compound with molecular formula C18H14FN3OS2 and molecular weight 371.06 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
4-[[5-(4-fluorophenyl)thieno[2,3-d]pyrimidin-4-yl]sulfanylmethyl]-3,5-dimethyl-1,2-oxazole
Also Known As: F1143-5780, AF-399/15128584, 4-(((5-(4-fluorophenyl)thieno[2,3-d]pyrimidin-4-yl)thio)methyl)-3,5-dimethylisoxazole, 4-({[5-(4-fluorophenyl)thieno[2,3-d]pyrimidin-4-yl]sulfanyl}methyl)-3,5-dimethyl-1,2-oxazole, 4-[[5-(4-fluorophenyl)thieno[2,3-d]pyrimidin-4-yl]sulfanylmethyl]-3,5-dimethyl-1,2-oxazole
| Molecular Formula | C18H14FN3OS2 |
|---|---|
| Molecular Weight | 371.06 g/mol |
| LogP | 5.39454 |
| Topological Polar Surface Area | 51.81 Ų |
| Hydrogen Bond Donors | 0 |
| Hydrogen Bond Acceptors | 6 |
| Rotatable Bonds | 4 |
| Exact Mass | 371.05624 |
| Heavy Atoms | 25 |
| Complexity | 1020.84985 |
Chemical Identifiers
| CAS Number | 315693-83-5 |
|---|---|
| SMILES | CC1=C(C(=NO1)C)CSC2=NC=NC3=C2C(=CS3)C4=CC=C(C=C4)F |
Product Overview
F1143-5780 (CAS 315693-83-5), with molecular formula C18H14FN3OS2 and molecular weight 371.06 g/mol. IUPAC: 4-[[5-(4-fluorophenyl)thieno[2,3-d]pyrimidin-4-yl]sulfanylmethyl]-3,5-dimethyl-1,2-oxazole.
Chemical Property Profile of F1143-5780
Property Insights of F1143-5780
The XLogP value of 5.39454 indicates that F1143-5780 is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. With a topological polar surface area (TPSA) of 51.81 Ų, F1143-5780 exhibits relatively low polarity, potentially indicating favorable cell membrane permeability. Following Lipinski's Rule of Five, F1143-5780 has 0 hydrogen bond donor(s) and 6 hydrogen bond acceptor(s), which may warrant consideration for formulation optimization.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of F1143-5780?
The CAS number of F1143-5780 is 315693-83-5.
What is the molecular formula of F1143-5780?
The molecular formula of F1143-5780 is C18H14FN3OS2.
What is the molecular weight of F1143-5780?
The molecular weight of F1143-5780 is 371.06 g/mol.
Where can I buy F1143-5780?
You can request a quote for F1143-5780 directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for F1143-5780?
Yes, KEHONG BIO provides custom synthesis services for F1143-5780 and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.