Ethyl 4-(4-fluorophenyl)-2-(1-naphthoylamino)-3-thiophenecarboxylate
TL;DR: Ethyl 4-(4-fluorophenyl)-2-(1-naphthoylamino)-3-thiophenecarboxylate (CAS 315682-84-9) is a chemical compound with molecular formula C24H18FNO3S and molecular weight 419.10 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
ethyl 4-(4-fluorophenyl)-2-(naphthalene-1-carbonylamino)thiophene-3-carboxylate
Also Known As: AF-399/15128463, ethyl 4-(4-fluorophenyl)-2-(1-naphthoylamino)-3-thiophenecarboxylate, ethyl 2-(1-naphthamido)-4-(4-fluorophenyl)thiophene-3-carboxylate, ethyl 4-(4-fluorophenyl)-2-(naphthalene-1-carbonylamino)thiophene-3-carboxylate
| Molecular Formula | C24H18FNO3S |
|---|---|
| Molecular Weight | 419.10 g/mol |
| LogP | 6.1364 |
| Topological Polar Surface Area | 55.4 Ų |
| Hydrogen Bond Donors | 1 |
| Hydrogen Bond Acceptors | 4 |
| Rotatable Bonds | 5 |
| Exact Mass | 419.09915 |
| Heavy Atoms | 30 |
| Complexity | 1225.6786 |
Chemical Identifiers
| CAS Number | 315682-84-9 |
|---|---|
| SMILES | CCOC(=O)C1=C(SC=C1C2=CC=C(C=C2)F)NC(=O)C3=CC=CC4=CC=CC=C43 |
Product Overview
Ethyl 4-(4-fluorophenyl)-2-(1-naphthoylamino)-3-thiophenecarboxylate (CAS 315682-84-9), with molecular formula C24H18FNO3S and molecular weight 419.10 g/mol. IUPAC: ethyl 4-(4-fluorophenyl)-2-(naphthalene-1-carbonylamino)thiophene-3-carboxylate.
Chemical Property Profile of Ethyl 4-(4-fluorophenyl)-2-(1-naphthoylamino)-3-thiophenecarboxylate
Property Insights of Ethyl 4-(4-fluorophenyl)-2-(1-naphthoylamino)-3-thiophenecarboxylate
The XLogP value of 6.1364 indicates that Ethyl 4-(4-fluorophenyl)-2-(1-naphthoylamino)-3-thiophenecarboxylate is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. With a topological polar surface area (TPSA) of 55.4 Ų, Ethyl 4-(4-fluorophenyl)-2-(1-naphthoylamino)-3-thiophenecarboxylate exhibits relatively low polarity, potentially indicating favorable cell membrane permeability. Following Lipinski's Rule of Five, Ethyl 4-(4-fluorophenyl)-2-(1-naphthoylamino)-3-thiophenecarboxylate has 1 hydrogen bond donor(s) and 4 hydrogen bond acceptor(s), which may warrant consideration for formulation optimization.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of Ethyl 4-(4-fluorophenyl)-2-(1-naphthoylamino)-3-thiophenecarboxylate?
The CAS number of Ethyl 4-(4-fluorophenyl)-2-(1-naphthoylamino)-3-thiophenecarboxylate is 315682-84-9.
What is the molecular formula of Ethyl 4-(4-fluorophenyl)-2-(1-naphthoylamino)-3-thiophenecarboxylate?
The molecular formula of Ethyl 4-(4-fluorophenyl)-2-(1-naphthoylamino)-3-thiophenecarboxylate is C24H18FNO3S.
What is the molecular weight of Ethyl 4-(4-fluorophenyl)-2-(1-naphthoylamino)-3-thiophenecarboxylate?
The molecular weight of Ethyl 4-(4-fluorophenyl)-2-(1-naphthoylamino)-3-thiophenecarboxylate is 419.10 g/mol.
Where can I buy Ethyl 4-(4-fluorophenyl)-2-(1-naphthoylamino)-3-thiophenecarboxylate?
You can request a quote for Ethyl 4-(4-fluorophenyl)-2-(1-naphthoylamino)-3-thiophenecarboxylate directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for Ethyl 4-(4-fluorophenyl)-2-(1-naphthoylamino)-3-thiophenecarboxylate?
Yes, KEHONG BIO provides custom synthesis services for Ethyl 4-(4-fluorophenyl)-2-(1-naphthoylamino)-3-thiophenecarboxylate and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.