Bromocolchicine
TL;DR: Bromocolchicine (CAS 31562-40-0) is a chemical compound with molecular formula C22H24BrNO6 and molecular weight 477.08 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
2-bromo-N-[(7S)-1,2,3,10-tetramethoxy-9-oxo-6,7-dihydro-5H-benzo[a]heptalen-7-yl]acetamide
Also Known As: Bromocolchicine, 2-bromo-N-[(7S)-1,2,3,10-tetramethoxy-9-oxo-6,7-dihydro-5H-benzo[a]heptalen-7-yl]acetamide, 2-bromo-n-[(7s)-1,2,3,10-tetramethoxy-9-oxo-5,6,7,9-tetrahydrobenzo[a]heptalen-7-yl]acetamide, Acetamide, 2-bromo-N-(5,6,7,9-tetrahydro-1,2,3,10-tetramethoxy-9-oxobenzo(a)heptalen-7-yl)-, (S)-, 2-bromanyl-N-[(7S)-1,2,3,10-tetramethoxy-9-oxidanylidene-6,7-dihydro-5H-benzo[a]heptalen-7-yl]ethanamide
| Molecular Formula | C22H24BrNO6 |
|---|---|
| Molecular Weight | 477.08 g/mol |
| LogP | 1.8 |
| Topological Polar Surface Area | 83.1 Ų |
| Hydrogen Bond Donors | 1 |
| Hydrogen Bond Acceptors | 6 |
| Rotatable Bonds | 6 |
| Exact Mass | 477.0787 |
| Heavy Atoms | 30 |
| Complexity | 761.0 |
Chemical Identifiers
| CAS Number | 31562-40-0 |
|---|---|
| SMILES | COC1=CC=C2C(=CC1=O)[C@H](CCC3=CC(=C(C(=C32)OC)OC)OC)NC(=O)CBr |
| InChIKey | AHQTYFABEKOZCI-HNNXBMFYSA-N |
Product Overview
Bromocolchicine (CAS 31562-40-0), with molecular formula C22H24BrNO6 and molecular weight 477.08 g/mol. IUPAC: 2-bromo-N-[(7S)-1,2,3,10-tetramethoxy-9-oxo-6,7-dihydro-5H-benzo[a]heptalen-7-yl]acetamide.
Chemical Property Profile of Bromocolchicine
Property Insights of Bromocolchicine
The XLogP value of 1.8 suggests moderate lipophilicity, balancing water solubility and membrane permeability for Bromocolchicine. The TPSA of 83.1 Ų falls within the moderate polarity range, balancing permeability and solubility for Bromocolchicine. Following Lipinski's Rule of Five, Bromocolchicine has 1 hydrogen bond donor(s) and 6 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of Bromocolchicine?
The CAS number of Bromocolchicine is 31562-40-0.
What is the molecular formula of Bromocolchicine?
The molecular formula of Bromocolchicine is C22H24BrNO6.
What is the molecular weight of Bromocolchicine?
The molecular weight of Bromocolchicine is 477.08 g/mol.
Where can I buy Bromocolchicine?
You can request a quote for Bromocolchicine directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for Bromocolchicine?
Yes, KEHONG BIO provides custom synthesis services for Bromocolchicine and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.