AF-399/15023013
TL;DR: AF-399/15023013 (CAS 315244-83-8) is a chemical compound with molecular formula C15H12F2N4O2 and molecular weight 318.09 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
6-amino-4-[2-(difluoromethoxy)phenyl]-3-methyl-2,4-dihydropyrano[2,3-c]pyrazole-5-carbonitrile
Also Known As: AF-399/15023013, 6-amino-4-[2-(difluoromethoxy)phenyl]-3-methyl-1,4-dihydropyrano[2,3-c]pyrazole-5-carbonitrile, 6-Amino-4-[2-(difluoromethoxy)phenyl]-1,4-dihydro-3-methylpyrano[2,3-c]pyrazole-5-carbonitrile, 6-amino-4-[2-(difluoromethoxy)phenyl]-3-methyl-4H-pyrano[3,2-d]pyrazole-5-carb onitrile, 6-amino-4-(2-(difluoromethoxy)phenyl)-3-methyl-1,4-dihydropyrano[2,3-c]pyrazole-5-carbonitrile
| Molecular Formula | C15H12F2N4O2 |
|---|---|
| Molecular Weight | 318.09 g/mol |
| LogP | 2.5377 |
| Topological Polar Surface Area | 96.95 Ų |
| Hydrogen Bond Donors | 2 |
| Hydrogen Bond Acceptors | 5 |
| Rotatable Bonds | 3 |
| Exact Mass | 318.09283 |
| Heavy Atoms | 23 |
| Complexity | 823.12463 |
Chemical Identifiers
| CAS Number | 315244-83-8 |
|---|---|
| SMILES | CC1=C2C(C(=C(OC2=NN1)N)C#N)C3=CC=CC=C3OC(F)F |
Product Overview
AF-399/15023013 (CAS 315244-83-8), with molecular formula C15H12F2N4O2 and molecular weight 318.09 g/mol. IUPAC: 6-amino-4-[2-(difluoromethoxy)phenyl]-3-methyl-2,4-dihydropyrano[2,3-c]pyrazole-5-carbonitrile.
Chemical Property Profile of AF-399/15023013
Property Insights of AF-399/15023013
The XLogP value of 2.5377 suggests moderate lipophilicity, balancing water solubility and membrane permeability for AF-399/15023013. The TPSA of 96.95 Ų falls within the moderate polarity range, balancing permeability and solubility for AF-399/15023013. Following Lipinski's Rule of Five, AF-399/15023013 has 2 hydrogen bond donor(s) and 5 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of AF-399/15023013?
The CAS number of AF-399/15023013 is 315244-83-8.
What is the molecular formula of AF-399/15023013?
The molecular formula of AF-399/15023013 is C15H12F2N4O2.
What is the molecular weight of AF-399/15023013?
The molecular weight of AF-399/15023013 is 318.09 g/mol.
Where can I buy AF-399/15023013?
You can request a quote for AF-399/15023013 directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for AF-399/15023013?
Yes, KEHONG BIO provides custom synthesis services for AF-399/15023013 and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.