F1443-5246
TL;DR: F1443-5246 (CAS 314282-71-8) is a chemical compound with molecular formula C18H20N4O5S and molecular weight 404.12 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
ethyl (E)-4-[4-[(4,6-dimethylpyrimidin-2-yl)sulfamoyl]anilino]-4-oxobut-2-enoate
Also Known As: F1443-5246, (E)-ethyl 4-((4-(N-(4,6-dimethylpyrimidin-2-yl)sulfamoyl)phenyl)amino)-4-oxobut-2-enoate, ethyl (E)-4-[4-[(4,6-dimethylpyrimidin-2-yl)sulfamoyl]anilino]-4-oxobut-2-enoate, ethyl 4-(4-{[(4,6-dimethyl-2-pyrimidinyl)amino]sulfonyl}anilino)-4-oxo-2-butenoate, (4,6-dimethyl-2-pyrimidinylamino)-p-[(E)-2-ethoxycarbonylethenylcarbonylamino]phenyl(oxo)-lambda-sulfaniumolate
| Molecular Formula | C18H20N4O5S |
|---|---|
| Molecular Weight | 404.12 g/mol |
| LogP | 1.95204 |
| Topological Polar Surface Area | 127.35 Ų |
| Hydrogen Bond Donors | 2 |
| Hydrogen Bond Acceptors | 7 |
| Rotatable Bonds | 7 |
| Exact Mass | 404.11545 |
| Heavy Atoms | 28 |
| Complexity | 980.88605 |
Chemical Identifiers
| CAS Number | 314282-71-8 |
|---|---|
| SMILES | CCOC(=O)/C=C/C(=O)NC1=CC=C(C=C1)S(=O)(=O)NC2=NC(=CC(=N2)C)C |
Product Overview
F1443-5246 (CAS 314282-71-8), with molecular formula C18H20N4O5S and molecular weight 404.12 g/mol. IUPAC: ethyl (E)-4-[4-[(4,6-dimethylpyrimidin-2-yl)sulfamoyl]anilino]-4-oxobut-2-enoate.
Chemical Property Profile of F1443-5246
Property Insights of F1443-5246
The XLogP value of 1.95204 suggests moderate lipophilicity, balancing water solubility and membrane permeability for F1443-5246. The TPSA of 127.35 Ų falls within the moderate polarity range, balancing permeability and solubility for F1443-5246. Following Lipinski's Rule of Five, F1443-5246 has 2 hydrogen bond donor(s) and 7 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of F1443-5246?
The CAS number of F1443-5246 is 314282-71-8.
What is the molecular formula of F1443-5246?
The molecular formula of F1443-5246 is C18H20N4O5S.
What is the molecular weight of F1443-5246?
The molecular weight of F1443-5246 is 404.12 g/mol.
Where can I buy F1443-5246?
You can request a quote for F1443-5246 directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for F1443-5246?
Yes, KEHONG BIO provides custom synthesis services for F1443-5246 and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.