N-(4-fluorophenyl)-2-(thiophen-2-yl)quinoline-4-carboxamide
TL;DR: N-(4-fluorophenyl)-2-(thiophen-2-yl)quinoline-4-carboxamide (CAS 314023-68-2) is a chemical compound with molecular formula C20H13FN2OS and molecular weight 348.07 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
N-(4-fluorophenyl)-2-thiophen-2-ylquinoline-4-carboxamide
Also Known As: ChemDiv1_001406, BAS 00730267, BIM-0027975.P001, N-(4-fluorophenyl)-2-(thiophen-2-yl)quinoline-4-carboxamide, N-(4-fluorophenyl)-2-(2-thienyl)-4-quinolinecarboxamide
| Molecular Formula | C20H13FN2OS |
|---|---|
| Molecular Weight | 348.07 g/mol |
| LogP | 4.5 |
| Topological Polar Surface Area | 70.2 Ų |
| Hydrogen Bond Donors | 1 |
| Hydrogen Bond Acceptors | 4 |
| Rotatable Bonds | 3 |
| Exact Mass | 348.07327 |
| Heavy Atoms | 25 |
| Complexity | 469.0 |
Chemical Identifiers
| CAS Number | 314023-68-2 |
|---|---|
| SMILES | C1=CC=C2C(=C1)C(=CC(=N2)C3=CC=CS3)C(=O)NC4=CC=C(C=C4)F |
| InChIKey | QSOYDLNLYHOQPB-UHFFFAOYSA-N |
Product Overview
N-(4-fluorophenyl)-2-(thiophen-2-yl)quinoline-4-carboxamide (CAS 314023-68-2), with molecular formula C20H13FN2OS and molecular weight 348.07 g/mol. IUPAC: N-(4-fluorophenyl)-2-thiophen-2-ylquinoline-4-carboxamide.
Chemical Property Profile of N-(4-fluorophenyl)-2-(thiophen-2-yl)quinoline-4-carboxamide
Property Insights of N-(4-fluorophenyl)-2-(thiophen-2-yl)quinoline-4-carboxamide
The XLogP value of 4.5 indicates that N-(4-fluorophenyl)-2-(thiophen-2-yl)quinoline-4-carboxamide is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. The TPSA of 70.2 Ų falls within the moderate polarity range, balancing permeability and solubility for N-(4-fluorophenyl)-2-(thiophen-2-yl)quinoline-4-carboxamide. Following Lipinski's Rule of Five, N-(4-fluorophenyl)-2-(thiophen-2-yl)quinoline-4-carboxamide has 1 hydrogen bond donor(s) and 4 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of N-(4-fluorophenyl)-2-(thiophen-2-yl)quinoline-4-carboxamide?
The CAS number of N-(4-fluorophenyl)-2-(thiophen-2-yl)quinoline-4-carboxamide is 314023-68-2.
What is the molecular formula of N-(4-fluorophenyl)-2-(thiophen-2-yl)quinoline-4-carboxamide?
The molecular formula of N-(4-fluorophenyl)-2-(thiophen-2-yl)quinoline-4-carboxamide is C20H13FN2OS.
What is the molecular weight of N-(4-fluorophenyl)-2-(thiophen-2-yl)quinoline-4-carboxamide?
The molecular weight of N-(4-fluorophenyl)-2-(thiophen-2-yl)quinoline-4-carboxamide is 348.07 g/mol.
Where can I buy N-(4-fluorophenyl)-2-(thiophen-2-yl)quinoline-4-carboxamide?
You can request a quote for N-(4-fluorophenyl)-2-(thiophen-2-yl)quinoline-4-carboxamide directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for N-(4-fluorophenyl)-2-(thiophen-2-yl)quinoline-4-carboxamide?
Yes, KEHONG BIO provides custom synthesis services for N-(4-fluorophenyl)-2-(thiophen-2-yl)quinoline-4-carboxamide and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.