![6-Chloro-2-[4-(2-methylbenzoyl)piperazin-1-YL]-4-phenylquinazoline structure](/static/products/3133/313398-54-8.webp)
6-Chloro-2-[4-(2-methylbenzoyl)piperazin-1-YL]-4-phenylquinazoline
TL;DR: 6-Chloro-2-[4-(2-methylbenzoyl)piperazin-1-YL]-4-phenylquinazoline (CAS 313398-54-8) is a chemical compound with molecular formula C26H23ClN4O and molecular weight 442.16 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
[4-(6-chloro-4-phenylquinazolin-2-yl)piperazin-1-yl]-(2-methylphenyl)methanone
Also Known As: BAS 01052673, AB00667730-01, F0381-1875, 6-CHLORO-2-[4-(2-METHYLBENZOYL)PIPERAZIN-1-YL]-4-PHENYLQUINAZOLINE, [4-(6-Chloro-4-phenyl-quinazolin-2-yl)-piperazin-1-yl]-o-tolyl-methanone
| Molecular Formula | C26H23ClN4O |
|---|---|
| Molecular Weight | 442.16 g/mol |
| LogP | 5.22102 |
| Topological Polar Surface Area | 49.33 Ų |
| Hydrogen Bond Donors | 0 |
| Hydrogen Bond Acceptors | 4 |
| Rotatable Bonds | 3 |
| Exact Mass | 442.15604 |
| Heavy Atoms | 32 |
| Complexity | 1283.7574 |
Chemical Identifiers
| CAS Number | 313398-54-8 |
|---|---|
| SMILES | CC1=CC=CC=C1C(=O)N2CCN(CC2)C3=NC4=C(C=C(C=C4)Cl)C(=N3)C5=CC=CC=C5 |
Product Overview
6-Chloro-2-[4-(2-methylbenzoyl)piperazin-1-YL]-4-phenylquinazoline (CAS 313398-54-8), with molecular formula C26H23ClN4O and molecular weight 442.16 g/mol. IUPAC: [4-(6-chloro-4-phenylquinazolin-2-yl)piperazin-1-yl]-(2-methylphenyl)methanone.
Chemical Property Profile of 6-Chloro-2-[4-(2-methylbenzoyl)piperazin-1-YL]-4-phenylquinazoline
Property Insights of 6-Chloro-2-[4-(2-methylbenzoyl)piperazin-1-YL]-4-phenylquinazoline
The XLogP value of 5.22102 indicates that 6-Chloro-2-[4-(2-methylbenzoyl)piperazin-1-YL]-4-phenylquinazoline is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. With a topological polar surface area (TPSA) of 49.33 Ų, 6-Chloro-2-[4-(2-methylbenzoyl)piperazin-1-YL]-4-phenylquinazoline exhibits relatively low polarity, potentially indicating favorable cell membrane permeability. Following Lipinski's Rule of Five, 6-Chloro-2-[4-(2-methylbenzoyl)piperazin-1-YL]-4-phenylquinazoline has 0 hydrogen bond donor(s) and 4 hydrogen bond acceptor(s), which may warrant consideration for formulation optimization.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of 6-Chloro-2-[4-(2-methylbenzoyl)piperazin-1-YL]-4-phenylquinazoline?
The CAS number of 6-Chloro-2-[4-(2-methylbenzoyl)piperazin-1-YL]-4-phenylquinazoline is 313398-54-8.
What is the molecular formula of 6-Chloro-2-[4-(2-methylbenzoyl)piperazin-1-YL]-4-phenylquinazoline?
The molecular formula of 6-Chloro-2-[4-(2-methylbenzoyl)piperazin-1-YL]-4-phenylquinazoline is C26H23ClN4O.
What is the molecular weight of 6-Chloro-2-[4-(2-methylbenzoyl)piperazin-1-YL]-4-phenylquinazoline?
The molecular weight of 6-Chloro-2-[4-(2-methylbenzoyl)piperazin-1-YL]-4-phenylquinazoline is 442.16 g/mol.
Where can I buy 6-Chloro-2-[4-(2-methylbenzoyl)piperazin-1-YL]-4-phenylquinazoline?
You can request a quote for 6-Chloro-2-[4-(2-methylbenzoyl)piperazin-1-YL]-4-phenylquinazoline directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for 6-Chloro-2-[4-(2-methylbenzoyl)piperazin-1-YL]-4-phenylquinazoline?
Yes, KEHONG BIO provides custom synthesis services for 6-Chloro-2-[4-(2-methylbenzoyl)piperazin-1-YL]-4-phenylquinazoline and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.