F0452-5481 structure

F0452-5481

TL;DR: F0452-5481 (CAS 313245-44-2) is a chemical compound with molecular formula C26H14F3N5O3S and molecular weight 533.08 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.

N-[2-(1,3-dioxoisoindol-2-yl)phenyl]-5-thiophen-2-yl-7-(trifluoromethyl)pyrazolo[1,5-a]pyrimidine-2-carboxamide

Also Known As: F0452-5481, N-(2-(1,3-dioxoisoindolin-2-yl)phenyl)-5-(thiophen-2-yl)-7-(trifluoromethyl)pyrazolo[1,5-a]pyrimidine-2-carboxamide, N-[2-(1,3-dioxo-2,3-dihydro-1H-isoindol-2-yl)phenyl]-5-(thiophen-2-yl)-7-(trifluoromethyl)pyrazolo[1,5-a]pyrimidine-2-carboxamide, N-[2-(1,3-dioxoisoindol-2-yl)phenyl]-5-thiophen-2-yl-7-(trifluoromethyl)pyrazolo[1,5-a]pyrimidine-2-carboxamide

CAS: 313245-44-2
Molecular Formula C26H14F3N5O3S
Molecular Weight 533.08 g/mol
LogP 5.5295
Topological Polar Surface Area 96.67 Ų
Hydrogen Bond Donors 1
Hydrogen Bond Acceptors 6
Rotatable Bonds 4
Exact Mass 533.07697
Heavy Atoms 38
Complexity 1726.8672

Chemical Identifiers

CAS Number 313245-44-2
SMILES C1=CC=C2C(=C1)C(=O)N(C2=O)C3=CC=CC=C3NC(=O)C4=NN5C(=CC(=NC5=C4)C6=CC=CS6)C(F)(F)F

Product Overview

F0452-5481 (CAS 313245-44-2), with molecular formula C26H14F3N5O3S and molecular weight 533.08 g/mol. IUPAC: N-[2-(1,3-dioxoisoindol-2-yl)phenyl]-5-thiophen-2-yl-7-(trifluoromethyl)pyrazolo[1,5-a]pyrimidine-2-carboxamide.

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Safety Data Sheet (MSDS / SDS) View the Laboratory Chemical Safety Summary (LCSS) on PubChem — includes GHS classifications, hazard statements, first aid measures, and handling precautions.
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Chemical Property Profile of F0452-5481

XLogP
5.5295
TPSA (Topological Polar Surface Area)
96.67
Hydrogen Bond Donors
1
Hydrogen Bond Acceptors
6
Rotatable Bonds
4
Heavy Atoms
38
Complexity
1726.8672
Exact Mass
533.07697
Monoisotopic Mass
533.07697
Data Source: Chemical property values are referenced from PubChem, the world's largest open chemistry database maintained by the National Center for Biotechnology Information (NCBI), U.S. National Library of Medicine.

Property Insights of F0452-5481

The XLogP value of 5.5295 indicates that F0452-5481 is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. The TPSA of 96.67 Ų falls within the moderate polarity range, balancing permeability and solubility for F0452-5481. Following Lipinski's Rule of Five, F0452-5481 has 1 hydrogen bond donor(s) and 6 hydrogen bond acceptor(s), which may warrant consideration for formulation optimization.

Frequently Asked Questions

What is the typical lead time for this product?
Lead time typically ranges from 3-7 business days for in-stock items. For larger quantities or custom orders, please contact us for specific lead times.
Can you provide samples for testing?
Yes, we offer sample quantities for quality testing. Please submit an inquiry with your requirements and we will arrange samples accordingly.
What documentation do you provide with the product?
We provide COA (Certificate of Analysis), MSDS (Material Safety Data Sheet), and technical data sheets with each shipment.
Do you ship internationally?
Yes, we ship to most countries worldwide. Shipping costs and delivery times vary by location. Please contact us for specific shipping information.

Frequently Asked Questions

What is the CAS number of F0452-5481?

The CAS number of F0452-5481 is 313245-44-2.

What is the molecular formula of F0452-5481?

The molecular formula of F0452-5481 is C26H14F3N5O3S.

What is the molecular weight of F0452-5481?

The molecular weight of F0452-5481 is 533.08 g/mol.

Where can I buy F0452-5481?

You can request a quote for F0452-5481 directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.

Does KEHONG BIO offer custom synthesis for F0452-5481?

Yes, KEHONG BIO provides custom synthesis services for F0452-5481 and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.

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