6-Azacytidine
TL;DR: 6-Azacytidine (CAS 3131-60-0) is a chemical compound with molecular formula C8H12N4O5 and molecular weight 244.08 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
5-amino-2-[(2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)oxolan-2-yl]-1,2,4-triazin-3-one
Also Known As: 6-Azacytidine, 6-Azacytidine (VAN), 6-Azacytosine riboside, Tox21_201231, 6-CHLORO-[3,4]-BIPYRIDINE
| Molecular Formula | C8H12N4O5 |
|---|---|
| Molecular Weight | 244.08 g/mol |
| LogP | -2.5 |
| Topological Polar Surface Area | 141.0 Ų |
| Hydrogen Bond Donors | 4 |
| Hydrogen Bond Acceptors | 6 |
| Rotatable Bonds | 2 |
| Exact Mass | 244.08076 |
| Heavy Atoms | 17 |
| Complexity | 384.0 |
Chemical Identifiers
| CAS Number | 3131-60-0 |
|---|---|
| SMILES | C1=NN(C(=O)N=C1N)[C@H]2[C@@H]([C@@H]([C@H](O2)CO)O)O |
| InChIKey | OZQDLJNDRVBCST-SHUUEZRQSA-N |
Patent-Derived Application Labels
Derived from 8 IPC patent classification(s) across the SureChEMBL global patent database.
Product Overview
6-Azacytidine (CAS 3131-60-0), with molecular formula C8H12N4O5 and molecular weight 244.08 g/mol. IUPAC: 5-amino-2-[(2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)oxolan-2-yl]-1,2,4-triazin-3-one.
Chemical Property Profile of 6-Azacytidine
Property Insights of 6-Azacytidine
The XLogP value of -2.5 indicates that 6-Azacytidine is hydrophilic (water-soluble), making it suitable for aqueous formulations and biological assay applications. The TPSA of 141.0 Ų indicates high polarity, suggesting 6-Azacytidine may have limited membrane permeability but good aqueous solubility. Following Lipinski's Rule of Five, 6-Azacytidine has 4 hydrogen bond donor(s) and 6 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of 6-Azacytidine?
The CAS number of 6-Azacytidine is 3131-60-0.
What is the molecular formula of 6-Azacytidine?
The molecular formula of 6-Azacytidine is C8H12N4O5.
What is the molecular weight of 6-Azacytidine?
The molecular weight of 6-Azacytidine is 244.08 g/mol.
Where can I buy 6-Azacytidine?
You can request a quote for 6-Azacytidine directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for 6-Azacytidine?
Yes, KEHONG BIO provides custom synthesis services for 6-Azacytidine and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.